Oral contraceptives increase platelet microparticle levels in normal-weight women with polycystic ovary syndrome.

CONCLUSION: In conclusion, PMP levels are increased in PCOS and further increase with OCP use. This effect could possibly contribute to the increased risk of venous thromboembolism associated with OCP use. However, further studies are needed to elucidate the exact role of PMPs in PCOS. PMID: 32078734 [PubMed - as supplied by publisher]
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research

Related Links:

Authors: López Castro J PMID: 32446683 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
At any given time, more than a third of Americans are on a specific diet, with weight loss as a leading reason. Most are going to be disappointed, because even when successful, lost weight is frequently regained within a few months. While most weight-loss diets can help you lose weight, they may be unsuccessful over the long run for a number of reasons. Some people don’t follow their diets carefully and don’t lose much weight even from the start. Others may go off the diet entirely after a while, because it’s too restrictive or the foods aren’t appealing. Some may engage in less physical activity as...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diet and Weight Loss Source Type: blogs
I'm stuck. Do I use the adversity essay to explain bad grades? I would prefer not to, because I cannot discuss the true circumstances of my bad grades 10 years ago (drinking problem), only discuss my growth in vague language, so it feels stupid. Current list of topics: "Overcame myself and my terrible grades" I was bullied as a kid for being fat, became obese as an adult, dx prediabetic, made drastic changes, attained healthy body weight, it was really hard. I can relate to my... Adversity prompt feedback - overcoming obesity vs bad grades vs sports injury
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Medical - MD Source Type: forums
CONCLUSION: As an easily accessible parameter, WBV might be a useful predictor of LVT formation within one year following acute anterior myocardial infarction. PMID: 32444531 [PubMed - as supplied by publisher]
Source: Biorheology - Category: Biochemistry Tags: Biorheology Source Type: research
Polycystic ovary syndrome (PCOS) is very prevalent and commonly treated with prothrombotic combined oral contraceptives (COC). Our aim was to systematically review the available evidence to evaluate the risk of venous thromboembolism (VTE) associated with PCOS, and whether observed increased risks may be explained by a higher prevalence of obesity and hormonal treatments.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research
Authors: Lee YJ, Jeong JE, Joo JK, Lee KS Abstract Idiopathic intracranial hypertension (IIH) is a rare neurologic disorder. It is also known as pseudotumor cerebri. The incidence of IIH is one to two per 100,000 population annually. The higher incidence is in obese women from 15 to 44 years. The main symptoms are headache and visual loss. It mostly affects women of childbearing age who are overweight or obese. There are many theories of pathogenesis of IIH, but precise pathogenesis is unknown. One of the causes of IIH is intracranial venous sinus thrombosis. It can cause increased cerebrospinal fluid (CSF) pressur...
Source: Clinical and Experimental Obstetrics and Gynecology - Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research
Semin Thromb HemostDOI: 10.1055/s-0035-1564837Polycystic ovarian syndrome (PCOS) affects 12 to 19% of women and has reproductive and metabolic features (endothelial dysfunction, increased diabetes, and cardiovascular risk factors). It also appears to have altered coagulation and fibrinolysis with a prothrombotic state with epidemiological evidence of increased venous thromboembolism. We aimed to comprehensively assess hemostasis in women with PCOS versus control women. In an established case–control cohort of lean, overweight, and obese women with (n = 107) and without PCOS (n = 67), with ...
Source: Seminars in Thrombosis and Hemostasis - Category: Hematology Authors: Source Type: research
STUDY QUESTION Are macroscopic and microscopic placental characteristics in a heterogeneous group of women diagnosed with polycystic ovary syndrome (PCOS) different from those of a low-risk general population? SUMMARY ANSWER Women with PCOS have significantly different microscopic placental characteristics compared with control women, independently from pregnancy complications. WHAT IS KNOWN ALREADY Non-obese women with PCOS who conceived spontaneously have a significantly reduced placental volume and weight, with more chronic villitis and intervillositis compared with healthy controls. STUDY DESIGN, SIZE, DURATION A su...
Source: Human Reproduction - Category: Reproduction Medicine Authors: Tags: Gynaecology Source Type: research
Conclusions Deletion of IR (i) increases platelet count and volume, (ii) does not cause platelet hyperactivity, and (iii) reduces GPVI-mediated platelet function and platelet priming by IGF-1 and IGF-2.
Source: Cardiovascular Research - Category: Cardiology Authors: Tags: Integrative physiology and pathophysiology Source Type: research
Conclusion It is already well known that the combined oral contraceptive pill ("the pill") is associated with increased risk of venous blood clots. It is also already known that risk can differ according to the type of progestogen in the pill. This study adds further evidence helping to quantify these risks. The study has numerous strengths. It has used two large GP databases covering large samples of the UK population, and containing reliable information on medical diagnoses and prescriptions made. The analyses were also adjusted for various confounders known to be associated with risk of blood clots. It demonst...
Source: NHS News Feed - Category: Consumer Health News Tags: Medication Source Type: news
More News: Eating Disorders & Weight Management | Endocrinology | Fortamet | Hormones | Metformin | Obesity | Ovaries | Polycystic Ovary Syndrome | Study | Thrombosis | Women