Gene is linked to deadly runaway fungal infection
Jean-Laurent Casanova, head of the Laboratory of Human Genetics of Infectious Diseases, and colleagues at Necker Medical School in Paris have discovered a genetic deficiency that in rare cases allows the dermatophyte fungus, which causes ringworm, to spread below the skin’s surface and onto the lymph nodes, bones, digestive tract and even the brain. More »
ConclusionFinally, our study revealed that the terbinafine resistance phenomenon might not be acquired by exposure to the drug but can be intrinsic. This is evidenced by the description of the terbinafine-resistant strains isolated from the asymptomatic animals.
DISCUSSION: Tinea on tattoos is rarely reported. We found ten additional cases in the literature, as well as five cases of less common fungal infections. These could be explained by the skin break created by the needle during tattooing resulting in an impaired skin barrier, or by accidental self-inoculation (e.g. foot-tattoos). The hypothesis of local immune deficiency induced by tattoo inks strikes us as rather improbable. Unlike usual cases of infections (pyogenic bacteria, mycobacteria, viral hepatitis), fungal infections are not related to a lack of hygiene on the part of the tattooist, but rather to contamination duri...
Conclusions: Skin NTDsand other poverty related skin infections were common at the dermatology service. Dermatological services could act as a good entry point for integrated management of skin NTDs. Future studies should assess how different preventive strategies like contact tracing, early diagnosis and mass drug administration can be integrated.
For those who claim that the Bible is the literal and inerrant word of God, and who claim to live by the Bible, Leviticus 13 and 14 ought to pose a considerable problem. Of course nobody who makes that claim is sincere. They just skip the embarrassing parts. Noah's ark is a fun story with animals. You can build a theme park around it. These chapters, however, are just deeply weird.It's important to note that " leprosy " here does not mean the disease which has been given that name in modern times, now more properly called Hansen's Disease. None of the symptoms described here correspond to those of Hansen's diseas...
CONCLUSION: Tinea capitis requires systemic antifungal treatment. Although topical antifungal therapies have minimal adverse events, topical antifungal agents alone are not recommended for the treatment of tinea capitis because these agents do not penetrate to the root of the hair follicles deep within the dermis. Topical antifungal therapy, however, can be used to reduce transmission of spores and can be used as adjuvant therapy to systemic antifungals. Combined therapy with topical and oral antifungals may increase the cure rate. PMID: 31906842 [PubMed - as supplied by publisher]
Conclusions: Our study revealed that toenail onychomycosis remains the most common superficial mycosis and T. rubrum is the most common pathogen. However, in a longer period of observation, a decrease in the number of tinea capitis cases and an increase in infections caused by T. tonsurans were noticed. Observed changes indicate the need for continuing studies to detect the upcoming epidemiological trends. PMID: 31839778 [PubMed]
AbstractPurpose of ReviewThis review summarizes the fungal literature currently available for adult tinea capitis (ATC), as well as providing data for clinical practice.Recent FindingsAvailable studies in ATC are scarce; however, they provide essential information for treating ATC.SummaryTreatment of TC is effective; however, it needs a minimum of 1 month to watch clinical efficacy. Systemic treatment is often needed to favor drug penetration to the deepest part of the hair follicle. The newest oral antifungal has higher efficacy rates than conventional therapy, as well as much shorter duration of treatment but at hi...
Ringworm is a highly contagious fungal infection of the skin. Here, find out how ringworm spreads, how long it remains contagious, and how to treat the infection.
Conclusion: Chicago sky blue and Calcofluor white staining are excellent methods for diagnosis of fungal infections, including those that cannot be confirmed using conventional methods. PMID: 31632123 [PubMed]
Tinea capitis, also called scalp ringworm, is a fungal infection. People may sometimes confuse it with other scalp conditions. Learn about its causes, symptoms, and treatments here.