Postoperative Outcomes of Patients with Obstructive Sleep Apnea Undergoing Cardiac Surgery

Publication date: Available online 20 February 2020Source: The Annals of Thoracic SurgeryAuthor(s): Bhargavi Gali, Amy E. Glasgow, Kevin L. Greason, Rebecca L. Johnson, Robert C. Albright, Elizabeth B. HabermannAbstractBackgroundObstructive sleep apnea (OSA) is associated with increased risk of postoperative complications in non-cardiac surgery, with limited literature on cardiac surgical patients. We compared perioperative outcomes of patients with OSA to those without OSA undergoing cardiac surgery.MethodsThis was a retrospective single center cohort study of adult patients who underwent cardiac surgery from January 2010 to April 2017. Our aim was to compare outcomes of patients with OSA to those without OSA including length of stay, readmissions, hospital mortality, and short-term outcomes.Results8612 patients during the study period included 2636 (30.6%) with OSA. Patients with OSA had a higher median length-of-stay (6 vs 5 days, P 7 days) length of stay (26.3% vs 23.0%, P
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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ConclusionIn this community-based sample of older adults, excessive daytime sleepiness was not associated with measures of arrhythmia burden. Future studies with objective measures of sleep are needed to further examine the role of sleep in the development and progression of arrhythmia burden.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
CONCLUSION: In this community-based sample of older adults, excessive daytime sleepiness was not associated with measures of arrhythmia burden. Future studies with objective measures of sleep are needed to further examine the role of sleep in the development and progression of arrhythmia burden. PMID: 32215831 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
Tatjana PS Abstract Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased risk of death, stroke and heart failure. The prevalence and incidence of AF is increasing due to better overall medical treatment, longer survival and increasing incidence of cardiometabolic and lifestyle risk factors. Treatment of AF and AF-related complications significantly increase health-care costs. In addition, use of conventional rhythm control strategies (i.g. antiarrhyhtmic drugs and catheter-ablation) is associated with limited efficacy for sinus rhythm maintenance and serious adverse effe...
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
ConclusionsPatients with AF who were diagnosed with OSA had significantly higher plasma visfatin levels which increased according to the severity of OSA. Furthermore, multivariate regression analysis identified visfatin concentration over 1.25  ng/mL, male sex, age over 59.1 years, and permanent AF as the factors showing independent correlation with OSA.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
CONCLUSIONS: Patients with AF who were diagnosed with OSA had significantly higher plasma visfatin levels which increased according to the severity of OSA. Furthermore, multivariate regression analysis identified visfatin concentration over 1.25 ng/mL, male sex, age over 59.1 years, and permanent AF as the factors showing independent correlation with OSA. PMID: 32170672 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
Abstract BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of postoperative complications in non-cardiac surgery, with limited literature on cardiac surgical patients. We compared perioperative outcomes of patients with OSA to those without OSA undergoing cardiac surgery. METHODS: This was a retrospective single center cohort study of adult patients who underwent cardiac surgery from January 2010 to April 2017. Our aim was to compare outcomes of patients with OSA to those without OSA including length of stay, readmissions, hospital mortality, and short-term outcomes. RESULTS: 86...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
The objective of this research article was to assess the trend of hospitalization, epidemiological characteristics and economic burden in the young adult, aged 18–45 years, presenting with atrial fibrillation.MethodsHospitalization data from the National Inpatient Sample between 2005 and 2015 were used to analyze prevalence of risk factors and financial burden in young adults with atrial fibrillation.ResultsFrom 2005 to 2015, a total of 260,080 admissions were included in the study. From 2005 to 2015, there was a decreasing trend of total admissions with atrial fibrillation among the age group of 18–45 years co...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
This study applied network pharmacology to identify 94 active components in the six TCM liver-regulating herbs and 182 corresponding targets from several databases and comprehensive literature studies, as well as retrieved AF combined with OSAHS-related targets. Cytoscape software was adopted to construct the component-component target network and component-putative target-AF combined with OSAHS target network. Then, we obtained 38 putative therapeutic targets against AF combined with OSAHS. After the production of a putative therapeutic target interaction network, topological analysis was adopted to determine the core tar...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
AbstractBackgroundWe have previously demonstrated the feasibility of a nurse ‐led risk factor modification (RFM) program for improving weight loss and obstructive sleep apnea (OSA) care among atrial fibrillation (AF) patients.ObjectiveWe now report its impact on arrhythmia outcomes in a subgroup of patients undergoing catheter ablation.MethodsParticipating patients with obesity and/or need for OSA management (high ‐risk per Berlin Questionnaire or untreated OSA) underwent in‐person consultation and monthly telephone calls with the nurse for up to 1 year. Arrhythmias were assessed by office ECGs and ≥2 wearable mon...
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionAmong patients with AF, OSA is an independent risk factor for MACNE and, more specifically, stroke/SE.Graphical Abstract
Source: American Heart Journal - Category: Cardiology Source Type: research
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