Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients.

CONCLUSION: This study emphasizes the role of CYP-related genes as major regulators of clopidogrel response, including the poorly-investigated CYP2C8 and CYP2C18.
PMID: 32077582 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - February 19, 2020 Category: Hematology Authors: Fontana P, Ibberson M, Stevenson B, Wigger L, Daali Y, Niknejad A, Mach F, Docquier M, Xenarios I, Cuisset T, Alessi MC, Reny JL Tags: J Thromb Haemost Source Type: research