Intravenous cyclophosphamide monthly pulses in refractory myasthenia gravis

ConclusionsCYC was effective in all patients with refractory MG for a mean of 9 months, with worsening thereafter, which could be associated with low cumulative dose. The symptomatic improvement with CYC was noted within the 1st month. We conclude that CYC is effective as an induction to remission therapy, although our data suggest it is not effective as a long-term therapy.

http://link.springer.com/10.1007/s00415-019-09622-4

Source: Journal of Neurology - February 21, 2020 Category: Neurology Source Type: research