Roles and Mechanisms of Hawthorn and Its Extracts on Atherosclerosis: A Review

Cardiovascular disease (CVD), especially atherosclerosis, is a leading cause of morbidity and mortality globally; it causes a considerable burden on families and caregivers and results in significant financial costs being incurred. Hawthorn has an extensive history of medical use in many countries. In China, the use of hawthorn for the treatment of CVD dates to 659 AD. In addition, according to the theory of traditional Chinese medicine, it acts on tonifying the spleen to promote digestion and activate blood circulation to dissipate blood stasis. This review revealed that the hawthorn extracts possess serum lipid-lowering, anti-oxidative, and cardiovascular protective properties, thus gaining popularity, especially for its anti-atherosclerotic effects. We summarize the four principal mechanisms, including blood lipid-lowering, anti-oxidative, anti-inflammatory, and vascular endothelial protection, thus providing a theoretical basis for further utilization of hawthorn.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research

Related Links:

Publication date: Available online 6 April 2020Source: Journal of Ginseng ResearchAuthor(s): Xiaoying Li, Xianhui Cheng, Baosheng Liao, Jiang Xu, Xu Han, Jinbo Zhang, Zhiwei Lin, Lianghai Hu
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Publication date: Available online 14 January 2020Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Renuka T. Rudra, Vitaly Gordin, Lihua Xu
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 21 November 2019Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Maria P. Volpato, Izabela C.A. Breda, Ravena C. de Carvalho, Caroline de Castro Moura, Laís L. Ferreira, Marcelo L. Silva, Josie R.T. Silva
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 7 April 2020Source: Integrative Medicine ResearchAuthor(s): Hyesook Lee, Hyun Hwang-Bo, Seon Yeong Ji, Min Yeong Kim, So Young Kim, Minji Woo, Young-Sam Keum, Jeong Sook Noh, Joung-Hyun Park, Bae-Jin Lee, Gi-Young Kim, Eui Kyun Park, Young-Chae Chang, You-Jin Jeon, Yung Hyun Choi
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
Publication date: Available online 6 April 2020Source: Revista Española de Cardiología (English Edition)Author(s):
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
Publication date: Available online 7 April 2020Source: Indian Heart JournalAuthor(s): Kewal Kanabar, Dinakar Bootla, Navjyot Kaur, C.R. Pruthvi, Darshan Krishnappa, Krishna Santosh, Vivek Guleria, Manoj Kumar Rohit
Source: Indian Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Indian Heart JournalAuthor(s): Samit Ghosal, Binayak Sinha, Jignesh Ved, Mansij Biswas
Source: Indian Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Indian Heart JournalAuthor(s): Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Ajitkumar Valaparambil
Source: Indian Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Canadian Journal of CardiologyAuthor(s): Mohammad I. Zia, Venkat Ramanan, Idan Roifman, Kim A. Connelly, Graham A. Wright, Nilesh R. Ghugre
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Canadian Journal of CardiologyAuthor(s): Philip Moons, Koen Luyckx, Corina Thomet, Werner Budts, Junko Enomoto, Maayke A. Sluman, Chun-Wei Lu, Jamie L. Jackson, Paul Khairy, Stephen C. Cook, Shanthi Chidambarathanu, Luis Alday, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Andrew S. Mackie, Samuel Menahem, Maryanne Caruana, Gruschen Veldtman
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
More News: Cardiology | Cardiovascular | China Health | Drugs & Pharmacology | Hawthorn | Heart