Contrast-Enhanced Ultrasound for Assessment of Local Hemodynamic Changes Following a Rodent Contusion Spinal Cord Injury.
CONCLUSION: We conclude that CEUS has the spatial and temporal sensitivity and resolution to visualize local tissue perfusion and vessel architecture, which maybe useful clinically to determine injury extent and severity in patients with SCI. PMID: 32074323 [PubMed - in process]
In this study, we tried to assess the modulatory effect of (S)-3,4-Dicarboxyphenylglycine (DCPG), a metabotropic glutamate receptor subtype 8 (mGluR8) agonist, in a model of chronic central neuropathic pain in male rats. We used a spinal cord contusion method (T6-T8) for the induction of chronic central neuropathic pain.Male Wistar rats were randomly assigned to 5 equal groups (n = 10 per group). Clips compression injury model was used to induce chronic central neuropathic pain. Three weeks after spinal cord injury DCPG, siRNA and normal saline were administered intra-ventrolaterally to the periaqueductal gray (P...
Publication date: Available online 4 April 2020Source: Life SciencesAuthor(s): Long Xu, Yin-Yao Tang, Xing-Lei Ben, Mao-Hua Cheng, Wei-Xiao Guo, Yun Liu, Zheng-Feng Lu, Jie-Lin Deng
CONCLUSIONS: 1. SCI individuals suffer mostly from lack of dynamic stability, which does not depend on their lesion levels. 2. It seems that this problem may be due to rehabilitation methods used to improve stability in these patients. 3. It is recommended that new methods of rehabilitation or assistive devices should be used to improve stability of these individuals. PMID: 32242525 [PubMed - in process]
Authors: Sato KL, Sanada LS, Silva MDD, Okubo R, Sluka KA Abstract Background: Transcutaneous electrical nerve stimulation (TENS), manual acupuncture (MA), and spinal cord stimulation (SCS) are used to treat a variety of pain conditions. These non-pharmacological treatments are often thought to work through similar mechanisms, and thus should have similar effects for different types of pain. However, it is unclear if each of these treatments work equally well on each type of pain condition. The purpose of this study was to compared the effects of TENS, MA, and SCS on neuropathic, inflammatory, and non-inflammatory ...
Conclusion: These findings indicated that individuals with greater sensory and motor loss had an increased risk of developing additional pressure injuries compared to individuals with less impairment. These results are meaningful for stakeholders interested in understanding factors associated with developing subsequent pressure injuries during the index rehabilitation stay and provide a foundation for future research in this area. PMID: 32233917 [PubMed - as supplied by publisher]
This study was designed to identify variables independently associated with prostate volume in men with chronic SCI.MethodsIn this cross-sectional study, prostate volume of 138 men with chronic (> 1 years) SCI, aged 54.5 (25th–75th percentile: 36.0–66.0) years, was evaluated with trans-rectal ultrasonography. All patients underwent a complete neurological exam, as well as biochemical and hormonal assessment, including total testosterone (TT) levels. Free testosterone levels were calcu lated (cFT) by the Vermeulen formula.ResultsThe median prostate volume was 23.4 mL. At the univariate anal...
Authors: Sengupta M, Gupta A, Khanna M, Rashmi Krishnan UK, Chakrabarti D PMID: 32235290 [PubMed]
Authors: Chakrabarti D, Gupta A PMID: 32235289 [PubMed]
Authors: Saha S PMID: 32235288 [PubMed]
Condition: Spinal Cord Contusion Intervention: Biological: Human Allogeneic Umbilical Cord Blood Mononuclear Cells (hUCBMCs) systemic (i.v.) infusions Sponsors: Sklifosovsky Institute of Emergency Care; National Medical Research Center for Cardiology, Ministry of Health of Russian Federation Completed