Biocatalytic synthesis of planar chiral macrocycles

We report a strategy for enantio- and atroposelective biocatalytic synthesis of planar chiral macrocycles. The macrocycles can be formed with high enantioselectivity from simple building blocks and are decorated with functionality that allows one to further modify the macrocycles with diverse structural features.

Source: ScienceNOW - February 19, 2020 Category: Science Authors: Gagnon, C., Godin, E., Minozzi, C., Sosoe, J., Pochet, C., Collins, S. K. Tags: Chemistry reports Source Type: news