The association between follicle size and oocyte development as a function of final follicular maturation triggering
Publication date: Available online 20 February 2020Source: Reproductive BioMedicine OnlineAuthor(s): Aya Mohr-Sasson, Raoul Orvieto, Shlomit Blumenfeld, Michal Axelrod, Danielle Mor-Hadar, Leonti Grin, Adva Aizer, Jigal HaasAbstractResearch QuestionTo study the association between follicle size and oocyte/embryo quality, as a function of different triggering mode for final follicular maturation.Study DesignA cohort study conducted in a single tertiary medical center between July 2018 and May 2019. All women undergoing controlled ovarian hyperstimulation with triggering using hCG, GnRH agonist, or Dual trigger (GnRH agonist + hCG) were included. Before ultrasound-guided follicular aspiration, follicles were measured and divided into three groups according to their maximal dimensional size: large: ≥16 mm, medium: 15 to 13 mm, and small: 13mm, however, mature oocytes achieved similar fertilization and top quality embryo rates. Triggering mode did not influence oocyte recovery rate in the different follicle size groups.
Publication date: Available online 31 March 2020Source: LWTAuthor(s): Feng Wang, Yizhong Zhang, Ling Xu, Haile Ma
Intravascular ultrasound (IVUS) assessment of cardiac allograft vasculopathy (CAV) provides diagnostic and prognostic information. Multivessel analysis has high sensitivity for detecting CAV, but is time consuming, costly and associated with procedural risks compared to single-vessel examination. We evaluated the regional distribution and plaque characteristics of CAV to guide clinical evaluation by IVUS.
Hepatic cirrhosis is a potential severe complication of chronic heart failure and has major implications on treatment options. In general, patients with cirrhosis are considered ineligible for isolated cardiac transplantation. Therefore, proper diagnosis of cirrhosis is paramount. The aim of this retrospective study is to explore the diagnostic value of abdominal ultrasound, hepatosplenic scan and abdominal computed tomography scan (CT scan) for liver disease secondary to advanced heart failure.
Everolimus (EVL) can be utilized after heart reduce calcineurin inhibitor (CNI) associated nephrotoxicity, due to cell cycle inhibitor adverse effects, and as adjunct therapy for rejection and cardiac allograft vasculopathy (TCAV). Since 2007, we have primarily considered converting from mycophenolate mofetil with standard-dose CNIs to EVL with low-dose CNIs for the following recipients: 1) recipients with impaired renal function; 2) those with increases in or an initially large maximal intimal thickness (MIT) on routine intravascular ultrasound (IVUS) examinations; 3) donor derived TCAV; and 4) those with MMF-related leukopenia.
Intravascular ultrasound (IVUS) has been used in adult heart transplant (HTX) recipients early after transplant to assess risk for long-term outcomes, along with differences in therapeutic targets for the treatment of cardiac allograft vasculopathy (CAV). Little is known about the utility of IVUS early after pediatric HTX. We evaluated the use of IVUS early (
AbstractPurpose of reviewThis review describes the recent advances and evolving techniques in endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy (SAA) and highlights the novel alternative approaches for pancreato-biliary interventions in this group of patients.Recent findingsThe limitations of ERCP in patients with SAA have led to the development of improved endoscopic devices and accessories, and alternative approaches for pancreato-biliary interventions. Dedicated short-type single and double balloon enteroscopes (BE) have been developed with increased maneuverability and la...
Angiography and intravascular ultrasound (IVUS) of the epicardial coronary vasculature are routinely undertaken for cardiac allograft vasculopathy (CAV) assessment. Microvascular disease is common in CAV and may occur independently of epicardial disease. The purpose of this study was to examine the relationship between microvascular disease, epicardial disease and microvascular dysfunction in heart transplant (HT) patients.
Cardiac allograft vasculopathy (CAV) is a leading cause of death and re-transplantation (tx). Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are increasingly used for earlier detection, but lengthen procedure time and cost, and are unsuitable in small children. Coronary angiography is routine in all age groups but may be subjectively interpreted. We hypothesized that serial analysis of quantitative coronary angiography (QCA) is possible in infants and children and may also predict disease progression.
Coronary artery vasculopathy (CAV) remains a significant limitation for long-term survival after heart transplantation (HT), observed in 30-45% of recipients by 5 years and 50-65% by 10 years post-HT. Despite the increased fidelity, the detection of CAV at the level of the vessel remains invasive and with various modalities used in CAV screening, the ability to detect sub-occlusive disease or disease in vessels less than 1.5 mm diameter remains problematic. Donor ‐derived, cell‐free DNA (dd‐cfDNA (AlloSure)), detected in recipient blood, has been established as a non-invasive marker of allograft injury, useful in the...
Coronary allograft vasculopathy (CAV) continues to be a common cause of morbidity and mortality in heart transplant recipients. Little is known about the timing of onset or progression of CAV after heart transplantation (HTx), or its relationship to donor acquired disease. We sought to assess the incidence of donor acquired disease and impact on disease progression in the first year post transplant.