GSE145656 Investigation of de novo mutations in a schizophrenia case-parent trio by induced pluripotent stem cell based in vitro disease-modelling: Convergence of schizophrenia and autism-related cellular phenotypes

Conclusions: The approach of reprograming case-parent tr ios represents a possibility of investigating disease-causing mutations and comparing cell lines with reduced variation in genetic background. Our results are indicative of an overlap between schizophrenia and autism-related phenotypes in the investigated family.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research