Novel kidney injury biomarkers in tropical infections: a review of the literature.

This study has increased the knowledge on the pathophysiology of kidney disease in the presence of these infections and has contributed to the early diagnosis of kidney injury, pointing to glomerular, endothelial and inflammatory involvement as the main causes of the mechanisms leading to nephropathy and clinical complications. Future perspectives comprise establishing long-term cohort groups to assess the development of kidney disease and the patients' survival, as well as the use of new biomarkers such as urinary exosomes to detect risk groups and to understand the progression of kidney injuries.
PMID: 32074217 [PubMed - in process]

Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2020 Category: Tropical Medicine Authors: Meneses GC, Silva Junior GBD, Tôrres PPBF, Castro VQ, Lopes RL, Martins AMC, Daher EF Tags: Rev Inst Med Trop Sao Paulo Source Type: research