Synchrotron X-ray boost delivered by Microbeam Radiation Therapy after conventional X-ray therapy fractionated in time improves F98 glioma control

Synchrotron microbeam radiation therapy (MRT) is based on the spatial fractionation of the incident, highly collimated synchrotron beam into arrays of parallel microbeams depositing several hundred grays. It appears relevant to combine MRT with a conventional treatment course, preparing a treatment scheme for future patients in clinical trials. The efficiency of MRT delivered after several broad beam (BB) fractions to palliate of F98 brain tumors in rats in comparison with BB fractions alone was evaluated in this study.

Source: International Journal of Radiation Oncology * Biology * Physics - February 19, 2020 Category: Radiology Authors: Marine Potez, Audrey Bouchet, M élanie Flaender, Claire Rome, Nora Collomb, Michael Grotzer, Michael Krisch, Valentin Djonov, Jacques Balosso, Emmanuel Brun, Jean A. Laissue, Raphaël Serduc Source Type: research