Common Antibiotics Linked To Increased Risk Of Birth Defects, Study Says

(CNN) — Taking some common antibiotics during the first trimester of pregnancy was linked with higher risk of birth defects, according to a new study. The study, published Wednesday in the medical journal BMJ, found an increased risk of birth defects in the children of women who were prescribed macrolides during the first three months of pregnancy compared to mothers who were prescribed penicillin. Macrolide antibiotics include erythromycin, clarithromycin and azithromycin, and they are used to treat infections, such as pneumonia, bronchitis and urinary, skin and sexually transmitted diseases. They are often prescribed for patients who are allergic to penicillin. According to the study, macrolides are one of the most frequently prescribed antibiotics in Western countries. The study analyzed data from 104,605 children born in the United Kingdom between 1990 and 2016 and who were born to mothers prescribed either penicillin or macrolides. Researchers looked for birth defects and neurodevelopmental disorders diagnosed later in life. The study found that prescribing macrolides to pregnant women during the first trimester increased the risk of major malformations to 28 of 1,000 births, compared 18 per 1,000 births with penicillin. Specifically, the risk of cardiac malformations was higher. The study did not find a link between macrolides prescription and neurodevelopmental disorders. There was also no associated risk between birth defects and macrolides prescribed before con...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Source Type: news

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Conclusion: Severe acute pancreatitis during pregnancy leads to a high rate of fetal mortality.Gestational trimester, delayed diagnosis, HTG, MOF, gestational diabetes mellitus, and preeclampsia are predictors of fetal loss. Therefore, close monitoring is essential for pregnancies complicated with HTG, diabetes mellitus, and hypertension. PMID: 32249649 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
DiscussionThis protocol extends to the first years of schooling age the evaluation of the neurotoxicant effect of Mercury and of the other heavy metals on children's neurodevelopment, adjusting for the potential confounders such as the lifestyles and the social economic status of children's families. Longitudinal analysis of neurodevelopment, assessed in different ages (18, 40 months and 7 years), are performed. PMID: 32249266 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
CONCLUSION: Differences between NHB and NHW men in the intake of certain nutrients may be related to chronic disease disparities. Future research should consider racial/ethnic differences in dietary intake among men and the impact these differences have on men's health. PMID: 32250708 [PubMed - as supplied by publisher]
Source: Public Health Reports - Category: International Medicine & Public Health Tags: Public Health Rep Source Type: research
Authors: Stolzman KA, Connors JM Abstract The field of critical care nursing is multidimensional and filled with opportunities to bring change to current practice. In the United States, nearly 13% of patients (range, 8%-24%) admitted to an intensive care unit (ICU) die during or after the admission (https://www.dartmouthatlas.org/interactive-apps/end-of-life-care/). Critical care nurses provide care at every stage of acute and chronic illness. Often this includes care of the patient and family at end of life, guided by palliative care principles supported by the national guidelines including the American Associatio...
Source: Dimensions in Critical Care Nursing - Category: Nursing Tags: Dimens Crit Care Nurs Source Type: research
Authors: Zangrilli A, Bavetta M, Bianchi L Abstract Introduction: Psoriasis is a chronic inflammatory systemic disease that affects 2% of the population and is associated with an important physical and physiological burden. About 0,5-2% of psoriatic cases onset during the pediatric age range, and often it's not diagnosed until adulthood. Adalimumab is an anti-tumor necrosis factor monoclonal antibody approved for use in children in 2008 and now it was used in several diseases in rheumatology, gastroenterology and in dermatology.Areas covered: The purpose of this article was to summarize what has been described in t...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
Boris Johnson still in intensive care; Chinese city of Wuhan officially reopens; cases in Africa pass 10,000. Follow the latest updates.Boris Johnson ‘stable’ in intensive care and not on ventilator, says No 10Australia coronavirus updates – liveAt a glance: latest developmentsSee all of our coronavirus coverage5.16amBSTI ’m close to being this insanepic.twitter.com/6qAc8YjvUA5.11amBSTSarah Boseley speaks toProf Trudie Lang about the outbreak on the continent and explores how a history of responding toEbola and other public health emergencies could help.Related:Covid-19: how are African countries co...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news Europe UK news US news Africa Middle East and North Africa Asia Pacific Infectious diseases Science Source Type: news
(Frontiers) Pregnant women who deliver early are more likely to have a varied vaginal microbiome, especially in their first trimester. Combining data from several studies, the researchers analyzed information across a wide range of women in terms of ethnicity and stage of pregnancy and also highlight the specific bacteria associated with premature births. The authors hope these findings could help identify women at higher risk of giving birth prematurely.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Conclusions: When compared with Kd27 BIW, Kd70 QW is the optimal dose that represents a cost-effective utilization of health care budget with incremental CE ratios well below the accepted willingness-to-pay thresholds in the US. PMID: 32249621 [PubMed - as supplied by publisher]
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
We report a case of a 39-yr-old woman who developed abnormal uterine bleeding 44 mo after her last recognized pregnancy. An endometrial curettage specimen demonstrated an APSN with some features concerning for an intermediate trophoblastic tumor. A hysterectomy specimen demonstrated residual APSN with foci consistent with emerging PSTT and ETT. This case illustrates the earliest form of PSTT and ETT arising in association with an APSN and supports interpretation of APSN as an intermediary lesion between typical PSN and intermediate trophoblastic tumors.
Source: International Journal of Gynecological Pathology - Category: Pathology Tags: PATHOLOGY OF THE CORPUS: CASE REPORTS Source Type: research
Despite the common perception that the human papilloma virus (HPV) is a requirement for the development of cervical cancer (CC), a considerable number of CCs test HPV negative. Presently, many countries are shifting to HPV primary CC screening, and it is of importance to increase the knowledge about the group of CCs that test HPV negative. The aim of this study was to reinvestigate a proportion of cervical tumors with a primary negative or invalid test result. Reinvestigation with repeated genotyping (targeting L1) was followed by analysis with an alternative target method (targeting E6/E7) on existing or additional tumor ...
Source: International Journal of Gynecological Pathology - Category: Pathology Tags: PATHOLOGY OF THE LOWER TRACT: ORIGINAL ARTICLES Source Type: research
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