Clinical worsening despite intravenous thrombolysis in acute ischemic stroke secondary to carotid plaque rupture

We report on a patient with acute ischemic stroke secondary to carotid plaque rupture who experienced plaque thrombosis and marked clinical worsening despite IVT. While the latter is the gold standard therapy optimal platelets inhibition should be guaranteed to allow a safe as possible carotid intervention. Hereby we discuss all available strategies to be considered in order to better individualized treatment decision-making.
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research