Chromoendoscopy meta-analysis: correcting subgroup analysis interpretation

Feuerstein et  al1 conclude that chromoendoscopy is superior to standard-definition white-light endoscopy (SDWLE) but not superior to high-definition white-light endoscopy (HDWLE) in patients with inflammatory bowel disease. They base this conclusion on an analysis of 2 subgroups (chromoendoscopy vs SDWLE and ch romoendoscopy vs HDWLE) within their meta-analysis of randomized trials of chromoendoscopy versus white-light endoscopy. However, their interpretation of this subgroup analysis is incorrect.

Source: Gastrointestinal Endoscopy - February 21, 2020 Category: Gastroenterology Authors: Loren Laine, Tonya Kaltenbach, Alan Barkun, Roy Soetikno Tags: Letter to the Editor Source Type: research