Noradrenaline acting on astrocytic β2-adrenoceptors induces neurite outgrowth in primary cortical neurons.
In conclusion, this study indicates a novel role for NA acting at glial β2-adrenoceptors to induce neuritic growth through the expression of soluble factors that elicit a neurotrophic action and increase neuronal complexity.
PMID: 24126345 [PubMed - as supplied by publisher]
Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Day JS, 'neill EO, Cawley C, Aretz NK, Kilroy D, Gibney SM, Harkin A, Connor TJ Tags: Neuropharmacology Source Type: research