The effects of intraperitoneal metoprolol administration on healing of bone defects in rat tibia: a pilot study

ConclusionMetoprolol did not reduce bone-active cytokine: IL-1 β, IL-6, and RANKL. It also did not elevate IL-10 expression levels. Thus, it does not appear to decrease osteoclastogenesis.Clinical relevanceResults from this animal model help us understand any effect of metoprolol on bone healing by potential contribution to different real-world clinical research.

http://link.springer.com/10.1007/s00784-019-02987-w

Source: Clinical Oral Investigations - February 21, 2020 Category: Dentistry Source Type: research