Use of LUCS (Light-Up Cell System) as an alternative live cell method to predict human acute oral toxicity

This study demonstrates that the LUCS test method could be relevant for assessing human acute oral toxicity with a simplified protocol adapted to commercially available fluorescence readers. We suggest that this new alternative method can be used for acute systemic toxicity testing in combination with other tests under European REACH and other regulations, wherever pertinent alternative methods are still lacking.Graphical abstract
Source: Toxicology Reports - Category: Toxicology Source Type: research