Physiological predictors of exertional oxygen desaturation in patients with fibrotic interstitial lung disease

In patients with fibrotic interstitial lung disease (ILD), hypoxaemia on exertion is frequent, and contributes to exercise intolerance, exertional dyspnoea and reduced quality of life [1–3]. Clinically significant exertional hypoxaemia is typically defined as a drop in transcutaneous arterial oxygen saturation (SpO2) to ≤88% on a 6-min walk test (6MWT) [4], and is associated with reduced survival in ILD patients [5].

Source: European Respiratory Journal - February 19, 2020 Category: Respiratory Medicine Authors: Alfieri, V., Crisafulli, E., Visca, D., Chong, W. H., Stock, C., Mori, L., de Lauretis, A., Tsipouri, V., Chua, F., Kouranos, V., Kokosi, M., Hogben, C., Molyneaux, P. L., George, P. M., Maher, T. M., Chetta, A. A., Sestini, P., Wells, A. U., Renzoni, E. Tags: Original Articles: Research letters Source Type: research