RadioPathomics Artificial Intelligence Model to Predict Tumor Regression Grading in Locally Advanced Rectal Cancer

Condition:   Rectal Cancer Intervention:   Sponsors:   Sixth Affiliated Hospital, Sun Yat-sen University;   The Third Affiliated Hospital of Kunming Medical College.;   Sir Run Run Shaw Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Conditions:   Locally Advanced Rectal Carcinoma;   Rectal Adenocarcinoma;   Stage II Rectal Cancer AJCC v8;   Stage IIA Rectal Cancer AJCC v8;   Stage IIB Rectal Cancer AJCC v8;   Stage IIC Rectal Cancer AJCC v8;   Stage III Rectal Cancer AJCC v8;   Stage IIIA Rectal Can cer AJCC v8;   Stage IIIB Rectal Cancer AJCC v8;   Stage IIIC Rectal Cancer AJCC v8 Inte...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Huang Y, Gu X, Ge K, Fu G, Chu J, Wei W Abstract Neoadjuvant chemoradiotherapy has been established as the standard treatment for patients with locally advanced rectal cancer. However, the role of radiotherapy (RT) has not been fully confirmed in advanced colon cancer (LACC). We postulated that patients with pathological T4N2 locally advanced colon cancer would benefit more from RT. 6715 pT4N2M0 colon cancer patients were included in the Surveillance, Epidemiology, and End Results (SEER) database. The primary endpoints were 5-year overall survival (OS) and cancer-specific survival (CSS). Propensity score m...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Authors: Wang Z, Liang J, Chen J, Mei S, Liu Q Abstract BACKGROUND AND OBJECTIVE: Anastomotic leakage is one of the most serious complications after laparoscopic low anterior resection Low Anterior Resection (LAR) for rectal cancers. The purpose of this study was to evaluate the effectiveness of a transanal drainage tube placed for the prevention of anastomotic leakage after laparoscopic LAR. METHODS: The clinical data of 220 patients with rectal cancer who underwent laparoscopic LAR using the double stapling technique Double Stapling Department of Colorectal Surgery, National Cancer Center/National Clinical Re...
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
Condition:   Rectum Cancer Intervention:   Procedure: 'Watch and Wait' Approach or Organ Preservation Sponsor:   Beijing Cancer Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Rectal Neoplasms Intervention:   Procedure: Treatment for local recurrence with surgery or other treatments Sponsor:   Sahlgrenska University Hospital, Sweden Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Cancer, Rectum Intervention:   Procedure: Anterior resection for upper rectal cancer in obese Sponsor:   Zagazig University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
SummaryOur younger rectal carcinoma cases had poorer pathologic criteria but the therapy was the crucial factor affecting their survival. Full course of radiotherapy was crucial for better OS of the younger group (P = 0.014), while chemotherapy was crucial for better DFS/PFS in both the young and old age groups (P = 0.00).
Source: Memo - Magazine of European Medical Oncology - Category: Cancer & Oncology Source Type: research
Conclusion: We revealed that higher WC is related to colorectal cancer risk, thus suggesting that abdominal obesity may be a risk factor for colorectal cancer in this East Asian population.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
This study will help to further define CRC as distinct entities depending on tumor location, as shown by the widespread differences in plasma protein profile and dysregulated pathways.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Condition:   Cancer, Rectum Intervention:   Procedure: Anterior resection for upper rectal cancer in obese Sponsor:   Zagazig University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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