RadioPathomics Artificial Intelligence Model to Predict Tumor Regression Grading in Locally Advanced Rectal Cancer
Condition: Rectal Cancer Intervention: Sponsors: Sixth Affiliated Hospital, Sun Yat-sen University; The Third Affiliated Hospital of Kunming Medical College.; Sir Run Run Shaw Hospital Recruiting
Publication date: December 2020Source: Cancer Epidemiology, Volume 69Author(s): Rita Peila, Rhonda S. Arthur, Thomas E. Rohan
Publication date: Available online 8 October 2020Source: European Journal of Surgical OncologyAuthor(s): Tian-Ming Gao, Dou-Sheng Bai, Jian-Jun Qian, Chi Zhang, Sheng-Jie Jin, Guo-Qing Jiang
Current guidelines on rectal cancer (RC) management recommend pre-operative MRI for loco-regional staging and CT for staging of metastases. This allows appropriate selection of patients for chemo-radiotherapy ...
ConclusionPET/MR provides a more precise assessment of the local extent of rectal cancers in evaluating cancer length, N status, and external sphincter involvement. PET/MR offers the opportunity to improve clinical decision-making, especially when evaluating low rectal tumors with possible external sphincter involvement.
ConclusionsThis study demonstrated the limited impact of laparoscopic surgical experience on the learning curve of robotic rectal cancer surgery, which was greater than previously reported curves.
AbstractPurposeSystemic chemotherapy (SC) before surgery is a potential treatment to improve survival in patients with advanced rectal cancer. However, the impact of SC on lateral lymph nodes (LLNs) remains unclear.MethodsA total of 78 patients with stage II/III low rectal cancer, who received 3-month oxaliplatin-based SC followed by LLN dissection (LLND) in principle, were analysed retrospectively. “Total lateral lymph node metastases (tLLNMs)” was defined as having either pathological LLNMs (pLLNMs) or lateral local recurrences (LLRs). Patients with the maximum short-axis size of LLNs ≥ 7 mm we...
ConclusionThis study suggests that multidisciplinary management is a potentially effective treatment strategy for isolated LNM. Since time to LNM, the T-stage, and histological type are prognostic factors, an active follow-up program for colorectal cancer is required.
Neoadjuvant chemotherapy and short-course radiotherapy followed by resection has been gaining recognition in the treatment of rectal cancer. Avelumab is a fully human immunoglobulin that binds Programmed Death...
Journal of Laparoendoscopic&Advanced Surgical Techniques, Ahead of Print.