Tight glycemic control in critically ill children
Hyperglycemia is a common metabolic derangement in critically ill patients. In 2001, investigators from Leuven, Belgium published results of a randomized study conducted in an adult surgical ICU testing the benefit of intensive insulin therapy, with the goal of maintaining serum glucose 80-110 mg/deciliter (N Engl J Med 2001;345:1359-67). This strategy, labelled “tight glycemic control,” resulted in a statistically detectable survival benefit compared with the more conventional approach of maintaining serum glucose values near 200 mg/deciliter.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Philip Toltzis Tags: The Editors' Perspectives Source Type: research