Management of hospitalised osteoporotic vertebral fractures

ConclusionClinical care pathways for the hospitalised VFF population lack standardisation in Ireland. Key challenges reported by orthopaedic doctors and physiotherapists relate to pain management, osteoporosis medication prescription, clarity on indications for bracing and a lack of fracture liaison services. Clinical guidelines, defined clinical care pathways and high-quality clinical research trials are required for VFF management.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research

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In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitoch...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractPurpose of ReviewThe purpose of this narrative review was to highlight rehabilitation-relevant aspects of cancer treatment and primarily musculoskeletal impairments and rehabilitation interventions among women with breast and gynecologic cancers. For breast cancer, we reviewed post-mastectomy pain syndrome, upper quadrant dysfunction, aromatase inhibitor musculoskeletal syndrome (AIMSS), and lymphedema. For gynecologic cancers, pelvic floor dysfunction, lymphedema, and insufficiency fractures were selected.Recent FindingsThe recent breast cancer rehabilitation literature evaluates the pathophysiology of impairments...
Source: Current Physical Medicine and Rehabilitation Reports - Category: Rehabilitation Source Type: research
Conclusions: This study delineated the causes of chronic pain and use of analgesics in a geriatric population, which may help further studies about this issue in the future. PMID: 32399112 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Osteoporotic fractures are a major cause of functional impairment, disability, pain, and mortality. However, the incidence and intensity of these adverse outcomes might be reduced if targeted state-of-the-art management of osteoporosis is applied. Comprehensive guidelines in osteoporosis should include recommendations about screening, diagnosis, treatment, and monitoring to allow their implementation in clinical practice [1]. Moreover, there is a need for country-specific guidelines because of differences in the epidemiology of the disease, health-care costs, and healthcare systems among countries.
Source: Maturitas - Category: Primary Care Authors: Source Type: research
ConclusionsPreviously unpublished associations were observed between clinical and radiological characteristics of fragility VF and several fracture risk factors. The results could lead to a better understanding of the complex relationships between these risk factors and clinical presentation, and should be considered when assessing patients with VF.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
Abstract The purpose of this review is to summarize the pathophysiology of complex regional pain syndrome (CRPS), the underlying molecular mechanisms, and potential treatment options for its management. CRPS is a multifactorial pain condition. CRPS is characterized by prolonged or excessive pain and changes in skin color and temperature, and/or swelling in the affected area, and is generally caused by stimuli that lead to tissue damage. An inflammatory response involving various cytokines and autoantibodies is generated in response to acute trauma/stress. Chronic phase pathophysiology is more complex, involving th...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
Conclusion: This review aims to evaluate up-to-date evidence of Wuqinxi for bone health in English or Chinese language studies, and explore whether Wuqinxi can be used as an adjuvant treatment for osteoporosis and osteopenia. Ethics and dissemination: Ethical approval is not required as the review is a secondary study based on published literature. The results of the study will be published in peer-reviewed publications and disseminated electronically or in print. Protocol registration number: INPLASY202040135.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
CONCLUSIONS: Qigong research publications have been increasing gradually. Reports on study types, participants, Qigong Intervention, and outcomes are diverse and inconsistent. There is an urgent need to develop a set of reporting standards for various interventions of Qigong. Further trials of high methodological quality with sufficient sample size and real world studies are needed to verify the effects of Qigong in health and disease management. PMID: 32444061 [PubMed - as supplied by publisher]
Source: Complementary Therapies in Medicine - Category: Complementary Medicine Authors: Tags: Complement Ther Med Source Type: research
CONCLUSIONS: Wound healing was accomplished without removal of the exposed deep hardware in a patient with comorbidities and post-surgical wound dehiscence. PMID: 32335519 [PubMed - in process]
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
Conclusions: Compliance with AAOS guidelines is reasonable, and it can be increased by following recommendations regarding: preoperative analgesia, femoral head type, blood transfusion threshold, home physical therapy, nutritional assessment, pain management, vitamin D and calcium supplementation, and osteoporosis treatment. Level of Evidence: Level III.
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Original Research Source Type: research
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