Role of Ca ²⁺ in Inhibiting Ischemia-Induced Apoptosis of Parathyroid Gland Cells in New Zealand White Rabbits.
CONCLUSIONS This study demonstrates that calcium supplementation inhibited the apoptosis of parathyroid cells following ischemic injury. PMID: 32071284 [PubMed - in process]
Conclusion: Our study showed low recurrence rates in patients with cN0 PTC pathologically confirmed as N1a after PCND. The RFS did not differ according to the extent of thyroid surgery. Considering the low recurrence rate and the surgical morbidity associated with thyroid surgery, less than TT with PCND may be considered for patients with cN0 unilateral PTC even with a pathologic staging of N1a after PCND. PMID: 33029478 [PubMed]
In this study, we show that18F-DCFPyl might detect neovasculature in advanced, metastatic differentiated thyroid cancer (DTC). We first stained the preserved lymph node samples of three patients with DTC who had undergone total thyroidectomy and neck dissection for cervical lymph node metastatic disease to identify PSMA expression, with the PSMA antibody (DAKO Monoclonal). Then, we performed18F-DCFPyl imaging in two other advanced DTC patients with elevated serum thyroglobulin (Tg), indicative of residual disease. We compared the findings with contemporaneous FDG PET/CT scan, conventional Imaging (CT,MRI) and whole-body sc...
Condition: Thyroid Nodule Intervention: Procedure: thyroidectomy Sponsor: Mahmoud Fahd Not yet recruiting
Conclusion: The results can contribute to an optimization of the radiological protection of patients submitted to RIT, as well as allow better logistics of their admission, which can lead to more appropriate accommodation for the patient with a better use of resources. PMID: 33020234 [PubMed - as supplied by publisher]
ConclusionLobectomy is sufficient for clinically solitary PTC patients with risk factors of ipsilateral occult carcinoma. For clinically solitary PTC patients with score ≥4, careful preoperative evaluations are required to rule out the contralateral occult carcinoma. Even if contralateral occult carcinoma is not detected preoperatively, TT is recommended for high-risk patients.
Condition: Thyroid Goiter Interventions: Procedure: total thyroidectomy; Procedure: subtotal thyroidectomy Sponsor: Assiut University Not yet recruiting
Publication date: Available online 6 October 2020Source: The American Journal of SurgeryAuthor(s): Ma Cheng, Christopher Dodoo, Eyas Alkhalili
CONCLUSIONS: Following diagnosis with PTC or an indeterminate thyroid nodule, many patients have strong emotional reactions and an impulse to "get it out" elicited by the word "cancer." This reaction can persist even after receiving education about the excellent prognosis. Understanding patients' response to diagnosis is critical because their emotional reactions likely pose a barrier to implementing guidelines recommending less extensive management for PTC. PMID: 33012267 [PubMed - as supplied by publisher]
ConclusionsThe results of the present study demonstrate that the mRNA encoding for the ACE-2 receptor is expressed in thyroid follicular cells, making them a potential target for SARS-COV-2 entry. Future clinical studies in patients with COVID-19 will be required for increase our understanding of the thyroid repercussions of SARS-CoV-2 infection.
The aim of this study is to examine the outcomes of outpatient thyroidectomy per the American Thyroid Association (ATA) statement on this procedure using the American College of Surgeons National Surgical Quality Improvement Project (NSQIP) database.