Role of Ca ²⁺ in Inhibiting Ischemia-Induced Apoptosis of Parathyroid Gland Cells in New Zealand White Rabbits.
CONCLUSIONS This study demonstrates that calcium supplementation inhibited the apoptosis of parathyroid cells following ischemic injury. PMID: 32071284 [PubMed - in process]
Conclusion In patients with papillary thyroid carcinoma, BRAFV600E mutation is associated with high-risk pathological characteristics and worsened disease-free survival.
Condition: Papillary Thyroid Carcinoma Intervention: Procedure: Total thyroidectomy and central neck dissection Sponsor: Bassem Mohamed Sieda Recruiting
Abstract Thyrotoxicosis is a general term for excess circulating and tissue thyroid hormone levels, whereas hyperthyroidism specifically denotes disorders involving a hyperactive thyroid gland (Graves disease, toxic multinodular goiter, toxic adenoma). Diagnosis and determination of the cause rely on clinical evaluation, laboratory tests, and imaging studies. Hyperthyroidism is treated with antithyroid drugs, radioactive iodine ablation, or thyroidectomy. Other types of thyrotoxicosis are monitored and treated with β-blockers to control symptoms given that most of these conditions resolve spontaneously. ...
This study aimed to compare the outcomes of TORT for papillary thyroid carcinomas smaller than 1 cm and 1 cm or larger.MethodsThe study analyzed 269 patients with papillary thyroid carcinoma who underwent TORT at Korea University Hospital, Korea between January 2001 and December 2017. Surgical outcomes and postoperative complications were compared.ResultsGroup 1 (tumor
ConclusionsAge less than 45 years, male sex, tumor diameter larger than 1 cm, microcalcifications, and US-detected LLN metastasis may preoperatively predict LN-prRLN metastasis.
Publication date: Available online 2 April 2020Source: The American Journal of SurgeryAuthor(s): Sophie Dream, Rongzhi Wang, Kelly Lovell, Pallavi Iyer, Herbert Chen, Brenessa Lindeman
CONCLUSION: CEUS qualitative analysis is superior to TI-RADS in evaluating the diagnostic performance of small, solid thyroid nodules. Qualitative analysis of CEUS has a significantly higher specificity for diagnosis of malignant thyroid nodules than TI-RADS. ADVANCES IN KNOWLEDGE: The 2017 version of TI-RADS has recently suggested the malignant stratification of thyroid nodules by ultrasound. In this paper we applied this system and CEUS to evaluate 185 nodules and compare the results with pathological findings to access the diagnostic performance. PMID: 32242748 [PubMed - as supplied by publisher]
AbstractHypocalcaemic cardiomyopathy is a rare form of dilated cardiomyopathy. The authors here present two cases in which symptomatic dilated cardiomyopathy was the result of severe hypocalcaemia. First, we report about a 26 ‐year‐old woman with primary hypoparathyroidism and then about a 74‐year‐old man with secondary hypoparathyroidism following a thyroidectomy. In both cases, the left ventricular systolic function improved after calcium supplementation. In the first case, a lack of compliance led to a repeate d decrease of both serum calcium level and left ventricular systolic function. The authors also present...
Publication date: Available online 29 March 2020Source: The American Journal of SurgeryAuthor(s): Eugene S. Kim, Ankush Gosain