Effects of quetiapine on behavioral changes and expression of myelin proteins in a chronic alcohol dependence rat model.

CONCLUSIONS: Chronic quetiapine treatment alleviated the damage induced by chronic ethanol exposure with regard to learning and memory ability and to brain white matter. Thus, quetiapine appears to be a potentially promising pharmacotherapy for the treatment of alcohol use disorder.
PMID: 32070690 [PubMed - as supplied by publisher]

Source: Behavioural Brain Research - February 14, 2020 Category: Neurology Authors: Han J, Wang G, Liu M, Chai R, Guo J, Zhang F, Lu C, Zhang Y, Wang H, Zhang R Tags: Behav Brain Res Source Type: research