A novel cross-species model of Barlow ’s disease to biomechanically analyze repair techniques in an ex vivo left heart simulator

Barlow ’s disease remains challenging to repair given the complex valvular morphology and lack of quantitative data comparing techniques. Though there have been recent strides in ex vivo evaluation of cardiac mechanics, to the best of our knowledge, there is no disease model that accurately simulates the morphology and pathophysiology of Barlow’s disease. The purpose of this study was to design such a model.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research