Facile and economical Miyaura borylation and one-pot Suzuki–Miyaura cross-coupling reaction

Publication date: Available online 18 February 2020Source: Inorganica Chimica ActaAuthor(s): Phongsakorn Boontiem, Supavadee KiatiseviAbstractFacile and economical method for Miyaura borylation reaction between B2pin2 and aryl bromides is reported. The catalytic system containing 2 mol% PdCl2(PPh3)2 and KOAc serves to enable borylations to occur under solvent-free and atmospheric conditions. The developed protocol can be applied to synthesize symmetrical and unsymmetrical biaryls via one-pot two-step Suzuki–Miyaura cross-coupling reaction and also offers the up-scalability.Graphical abstract
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
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