SAPHO Syndrome from Hidradenitis Suppurativa

Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research

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Condition:   Hidradenitis Suppurativa Interventions:   Procedure: Excision of HS followed by NPWTi;   Procedure: Excision of HS followed by NPWT Sponsors:   Royal Free Hospital NHS Foundation Trust;   KCI Europe Holding B.V. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity. The pilosebaceous unit is a site for production and metabolism of a number of steroid hormones, including stress and sex hormones. This is an overview of the important role that the cutaneous HPA-like-axis plays in the pathogenesis and treatment of inflammatory pilosebaceous disorders, including acne, rosacea, seborrheic dermatitis, and hidradenitis suppurativa.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
We present a 26-year-old man with a history of pemphigus foliaceus (PF) who developed large draining nodules with scarring and sinus tracts, compatible with follicular occlusion triad, preferentially at areas previously affected by PF thirteen months after treatment with rituximab. To the authors' knowledge there are no reported cases of follicular occlusion triad or HS manifesting as an isotopic response. However, one member of the triad, HS, has been reported to occur infrequently following the use of biologic agents...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
CONCLUSIONS: The description of discharge symptoms experienced by many patients is similar to the description of symptoms of an umbilical pilonidal sinus (UPS). This is a condition with a morphology reminiscent to that of HS because it is defined by sinus tract formation triggered by hair penetrating the umbilical skin. UPS could be an explanation for umbilical HS symptom. PMID: 32206815 [PubMed - in process]
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder. Previous studies have yielded divergent results on the prevalence of depression and anxiety in HS patients.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
The ICAReB platform of Institut Pasteur provides access to human bio-resources for academic and private research teams worldwide, essentially in the fields of infection, immunity and neurosciences. More than 134,000 human quality controlled, duly annotated samples (mainly whole-blood derived products, but also stool, urine, saliva, swabs ….), from both healthy and diseased cohorts with open, regulated access, are available upon request. Both clinical investigation and biobanking activities are certified following ISO 9001:2015 and NF S96-900:2011 standards, respectively. ICAReB is a member of PIBnet (Pasteur Interna...
Source: Open Journal of Bioresources - Category: Biotechnology Source Type: research
The authors would like to correct the error in publication which is mentioned below.
Source: Dermatology and Therapy - Category: Dermatology Source Type: research
Publication date: Available online 20 March 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): J.M. Rueda Carnero, D. Nieto Rodríguez, R. de Lucas Laguna, M. Feito Rodríguez
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
This study sought to describe Body Image Quality of Life (BI-QoL) in patients with hidradenitis suppurativa and to compare it with patients with other skin diseases (controls). A total of 285 participants were recruited, 141 with hidradenitis suppurativa and 144 controls, at the Department of Dermatology at Zealand University Hospital, Denmark (during 2017-18). The Danish "Body Image Quality of Life Inventory" questionnaire measured BI-QoL. Patients with hidradenitis suppurativa had significantly lower mean BI-QoL than controls: Hidradenitis suppurativa BI-QoL (standard deviation; SD) -0.87 (0.98) vs. control BI-...
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
AbstractPurpose of ReviewOngoing investigations of the human skin microbiome strongly suggest a connection to skin diseases and skin health. This review provides an overview of recent literature on the skin microbiome in relation to skin diseases, with a specific focus on common inflammatory skin conditions, such as atopic dermatitis, psoriasis, hidradenitis suppurativa, acne, and rosacea.Recent FindingsIn healthy subjects, the skin microbiome mediates fundamental processes involving the immune response and epidermal development and differentiation. Microbiome characteristics in inflammatory skin diseases differ depending ...
Source: Current Dermatology Reports - Category: Dermatology Source Type: research
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