Common Plastics Chemicals Linked to Autism Traits in Young Boys

WEDNESDAY, Feb. 19, 2020 -- Young boys whose mothers were exposed to chemicals known as phthalates while pregnant may face an increased risk for developing behaviors associated with autism, a new study warns. Phthalates are chemicals found in many...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Abstract Preeclampsia is a dangerous hypertensive disorder of pregnancy with known links to negative child health outcomes. Here, we review epidemiological and basic neuroscience work from the past several decades linking prenatal preeclampsia to altered neurodevelopment. This work demonstrates increased rates of neuropsychiatric disorders [e.g., increased autism spectrum disorder, attention deficit hyperactivity disorder (ADHD)] in children of preeclamptic pregnancies, as well as increased rates of cognitive impairments [e.g., decreased intelligence quotient (IQ), academic performance] and neurological disease (e...
Source: Trends in Neurosciences - Category: Neuroscience Authors: Tags: Trends Neurosci Source Type: research
Abstract Autism is a neuropathology characterized by behavioral disorders. Considering that oxidative stress is involved in the pathophysiology of this disease, we evaluated the effects of quercetin, a flavonoid with antioxidant and neuroprotective properties, in an experimental model of autism induced by valproic acid (VPA). Twelve pregnant female rats were divided into four groups (control, quercetin, VPA, VPA+quercetin). Quercetin (50 mg/kg) was administered orally to the animals from gestational days 6.5 to 18.5, and VPA (800 mg/kg) was administered orally in a single dosage on gestational day 12.5. Behavioral...
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Tags: Int J Dev Neurosci Source Type: research
Maternal smoking of traditional or electronic cigarettes during pregnancy, which constitutes developmental nicotine exposure (DNE), heightens the risk of neurodevelopmental disorders including ADHD, autism, an...
Source: Epigenetics and Chromatin - Category: Genetics & Stem Cells Authors: Tags: Research Source Type: research
Conclusion When analyzing the risk-benefit of folic acid supplementation at the recommended doses, 0.4 to 0.8 mg/day, it is concluded that the benefits outweigh the possible risks of developing ASD.
Source: Jornal Brasileiro de Psiquiatria - Category: Psychiatry Source Type: research
This study investigated whether antenatal exposure to antidepressants (ADs) increases the risks of autism spectrum disorders (ASD), attention deficit/hyperactivity disorders (ADHD), schizophrenia and other mental illnesses, and cognitive and developmental deficits in infants or preschool children. PubMed, EMBASE, BIREME/BVS databases were searched to identify studies examining associations of ADs in pregnancy with neurodevelopmental and psychiatric disorders. Twenty studies addressed ASD and/or ADHD risks while 30 focused on developmental and cognitive deficits in infants or preschool children. Most studies detected no ass...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research
Alan Brown’s research links infections, chemical exposures, and inflammation in pregnancy to offspring’s schizophrenia, autism, and more. (read more)
Source: Environmental Factor - NIEHS Newsletter - Category: Environmental Health Source Type: news
Autism spectrum disorder is a neurodevelopmental disorder characterized by reduced social interactions, impaired communications, and stereotypic and repetitive behavior with different degrees of severity. The etiology of autism spectrum disorder is unknown, although the interaction of genetic and environmental factors is believed to play a fundamental role in the process. The main aim of this narrative review is to discuss the current knowledge about the interrelationships between vitamin D deficiency during pregnancy and autism spectrum disorder development. Literature analysis showed that vitamin D supplementation during...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Associations Between Broader Autism Phenotype and Dietary Intake: A Cross-Sectional Study (Japan Environment &Children's Study). J Autism Dev Disord. 2020 Jan 29;: Authors: Hirokawa K, Kimura T, Ikehara S, Honjo K, Ueda K, Sato T, Iso H, Japan Environment &Children’s Study Group Abstract The purpose of the present study was to investigate associations of dietary intake including vitamin D, folate, and n-3 and n-6 polyunsaturated fatty acids (PUFA) in pregnant women with broad autism phenotype (BAP). The Japan Environment and Children's Study is a government-funded birth cohort study. All...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
Publication date: Available online 21 January 2020Source: Journal of Hazardous MaterialsAuthor(s): Tianyu Dong, Quanquan Guan, Weiyue Hu, Mingzhi Zhang, Yuqing Zhang, Minjian Chen, Xinru Wang, Yankai XiaAbstractGlufosinate ammonium (GLA) is a widely used organophosphate herbicide, which could be commonly detected in body fluids of both pregnant women and newborns. Existing evidences indicate that GLA has reproductive toxicity, while data concerning the effects of prenatal GLA exposure on neurodevelopment is rather limited. Here we employed a mouse model exposed to GLA prenatally. Reduced locomotor activity, impaired memory...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
AbstractObjectiveTo evaluate the long-term pediatric neuropsychiatric morbidity of children born to obese patients.Study designA population-based cohort analysis was performed comparing all deliveries of obese (maternal pre-pregnancy body mass index of 30  kg/m2 or more) and non-obese patients between 1991 and 2014 at a single tertiary medical center. Hospitalizations of the offspring up to the age of 18  years involving neuropsychiatric morbidities were evaluated according to a pre-defined set of ICD-9 codes, including autistic, eating, sleeping and movement disorders, cerebral palsy, developmental disorders, an...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
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