Long-term outcomes in patients with encapsulating peritoneal sclerosis managed with nutritional support.

CONCLUSION: Long-term survival following EPS managed conservatively with nutritional support is feasible, with the majority no longer requiring nutritional support and having a quality of life similar to other patients with ESKD. PMID: 32067553 [PubMed - as supplied by publisher]
Source: Peritoneal Dialysis International - Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research

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When Dr. Mark Lewis has to tell a cancer patient they’re dying, he tries to do so as compassionately as possible, usually offering a hug or a hand to hold. The thought of doing so by phone, he says, once felt heartbreakingly impersonal. But in the face of the current COVID-19 pandemic, the Salt Lake City-based gastrointestinal oncologist has had to do many things that make his “conscience weigh heavy.” He’s delivered bad news virtually, to limit the possibility of spreading the virus. He’s delayed chemotherapy for patients who—he hopes—can wait, knowing the treatment would wipe out...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Magazine Source Type: news
AbstractThis review appraises the current literature on carcinogenic risks in anti-neutrophilic cytoplasmic autoantibody (ANCA) associated vasculitis (AAV). Patients with AAV are often at increased risk of developing non-melanoma skin carcinomas (NMSCs), haematological malignancies, bladder, breast, lung, prostate, and colorectal carcinomas. Reported cancer incidence in these patients ranged from 10 to 26%. Cancer risks at the time of diagnosis of AAV and disease outcomes along the trajectory of AAV that may lead to chronic kidney disease (CKD); dialysis and transplantation are summarized. Inherent carcinogenic risks as pa...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
When asked how the coronavirus (COVID-19) pandemic is impacting patients in need of an organ transplant, Sridhar Tayur said there is good news and bad news on that front. Tayur is the Ford distinguished research chair and professor of operations management at Carnegie Mellon University’s Tepper School of Business, and he has been paying close attention to the subject of organ transplants during the current crisis.  "The good news is that transplants are considered critical surgeries and therefore CMS [Centers for Medicare and Medicaid Services]Â&n...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
WEDNESDAY, March 25, 2020 -- The distance from a patient residence to transplant center seems not to impact transplant referral and evaluation initiation among those with end-stage kidney disease, according to a study published online March 24 in...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
We present a case of Epstein-Barr virus positive monomorphic plasma cell myeloma type PTLD that developed 10 months after cardiac transplant in an 18-month-old boy. The bone marrow showed replacement by about 20% to 40% lambda-restricted plasmacytoid lymphocytes and plasma cells (by immunohistochemistry and flow cytometry, respectively). His serum free lambda to kappa light chain ratio was>300, comparable to that seen in myeloma in nontransplant patients. The neoplastic cells were Epstein-Barr virus small RNA positive by in situ hybridization. He was treated with rituximab in combination with ganciclovir, intravenous im...
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
AbstractPurpose of ReviewLiving donor kidney transplantation (LDKT) remains the treatment of choice for suitable candidates with advanced kidney disease. Despite excellent outcomes for living kidney donors, the rate of living kidney donation has remained relatively stable over the past decade despite the growing number of those in need of kidney transplants. Telehealth may represent an opportunity to increase access to evaluation and donation for living donor candidates and improve care and follow-up of living donors. This review discusses current and potential opportunities in the utilization of telehealth throughout the ...
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research
AbstractPurpose of ReviewAdvances in renal regenerative medicine are crucial to address the increased rate of kidney disease. Clinicians and researchers are investigating new renal therapeutics aimed at promoting endogenous repair and/or at designing new technologies for organ and tissue regeneration. This review explores the potential promises and limitations of recent renal regenerative medicine approaches.Recent FindingsCurrent research directions include efforts to delay and deter acute and chronic kidney disease progression by exploiting the immune-modulatory and tissue regenerative properties of pharmacology agents, ...
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research
Four times a year, the Science Translational Medicine editors select recently published articles across the Science family of journals and highlight interesting translational ties. These short write-ups identify common links between disparate diseases; technologies and research approaches that could prove complementary; and biomedical insights that may inform therapies or treatments. This quarter’s articles cover cytokine-based therapies, GLP-1 receptors in metabolic disease, oncoproteins and checkpoint blockade, imaging insights into subcellular structures, engineered T cell treatments, and kidney transplant rejection.
Source: Science Translational Medicine - Category: Biomedical Science Tags: Editors ' Choice Source Type: research
The fate of transplanted kidneys is substantially influenced by graft quality, with transplantation of kidneys from elderly and expanded criteria donors (ECDs) associated with higher occurrence of delayed graft function, rejection, and inferior long-term outcomes. However, little is known about early molecular fingerprints of these events in different donor categories. Borderline changes represent the most frequent histological finding early after kidney transplantation. Therefore, we examined outcomes and transcriptomic profiles of early-case biopsies diagnosed as borderline changes in different donor categories. In this ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
DR KENNETH L BRAYMAN (Charlottesville, VA): This is a comprehensive and timely retrospective analysis of patient survival after liver transplantation in patients with chronic kidney disease. The challenges associated with the inability to predict native renal recovery after liver transplantation persist, and this complicates the debate over allocation of scarce resources such as kidneys from deceased donors. The data presented today informed the debate, and we thank the authors for their contribution in providing the manuscript for my review ahead of time.
Source: Journal of the American College of Surgeons - Category: Surgery Tags: Southern surgical association article Source Type: research
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