Experience of BRCA1/2 mutation-negative young women from families with hereditary breast and ovarian cancer: a qualitative study.

CONCLUSIONS: By eliciting detailed patient narratives we have begun to show that this generation of BRCA mutation-negative young women is likely still affected by the degree of cancer history in their family, even with their understanding of the genetic contribution to disease. Larger studies with tightened participant characteristics, as well as studies involving women from different cultural backgrounds, are needed to further define the experience and needs of true negative young women from HBOC families.
PMID: 24131499 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - October 16, 2013 Category: Cancer & Oncology Authors: Macrae L, de Souza AN, Loiselle CG, Wong N Tags: Hered Cancer Clin Pract Source Type: research