Subependymal Giant-cell Astrocytoma Masquerading as Restrictive Eating Disorder and Depression in an Adolescent

by Alicia Barnes, DO, MPH; Maggie M. Wang, BS; Jordan Feltes, BS; Je Ko, MD, PhD; and Miguel A. Guzman, MD Drs. Barnes and Ko are with the Department of Psychiatry, Saint Louis University School of Medicine in St. Louis, Missouri. Ms. Wang and Feltes are with the Saint Louis University School of Medicine in […] The post Subependymal Giant-cell Astrocytoma Masquerading as Restrictive Eating Disorder and Depression in an Adolescent appeared first on Innovations in Clinical Neuroscience.
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Depression Early Release Articles Eating Disorders Psychiatry adolescent astrocytoma brain neoplasms Feeding and eating disorders Source Type: research

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In this study, investigate whether there is an association between GSDMA (rs7212938, T/G) and GSDMB (rs7216389, T/C) at locus 17q21.2 and risk of Allergic Rhinitis among Jordanians. Also we aimed to determine if there is an association between such polymorphisms and the IgE level. METHODS: The study included 112 rhinitis patients and 111 Healthy controls. Gasdermin A (GSDMA) (rs7212938, T/G) and Gasdermin B (rs7216389, T/C) polymorphisms were genotyped using the PCR-RFLP method. RESULTS: On the genotype level, three analysis models were applied namely co-dominant, dominant and recessive genotypes. GSDMB CC genotype...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Resumo O presente ensaio busca discutir as implica ções do isolamento social devido à pandemia do COVID-19 para o uso intensivo da internet entre crianças e adolescentes e suas possíveis consequências para a prática de violências autoinflingidas. Discutimos brevemente o potencial ansiogênico e a reprodução de um “ medo global ” que se consolidam com a exposi ção maciça e sem mediação dos conteúdos consumidos, que podem aumentar as vulnerabilidades para estresse e ideações suicidas. C...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
Conditions:   Chronic Pain;   Depression, Anxiety;   Opioid Use Interventions:   Other: cCBT;   Other: m-Education Sponsor:   University of Pittsburgh Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Breast Cancer;   Circadian Rhythms;   Fatigue;   Sleep Disturbance;   Cognitive Impairment;   Inflammatory Response;   Depression Interventions:   Device: Light Glasses (Experimental);   Device: Light Glasses (Comparison) Sponsors:   Reykjavik University;   The Icelandic Centre for Research Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Trauma, Psychological;   Depression, Anxiety;   PTSD Intervention:   Behavioral: BEAR Sponsor:   Stanford University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Chronic Pain;   Depression, Anxiety;   Sleep;   Quality of Life Intervention:   Other: Neurofeedback training Sponsors:   Exsurgo Rehab Limited;   East Midlands Spine Ltd;   PhysioFunction Ltd Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Fatigue;   Depression, Anxiety;   Insomnia;   Hot Flashes;   Quality of Life Intervention:   Other: Acupuncture; based on Tradidtional Chinese Medicine Sponsors:   Kristiania University College;   Norwegian Cancer Society;   University of Bergen;   Memorial Sloan Kettering Cancer Center;   Dana-Farber Cancer Institute;   University Hospital, Akershus;   University of York;   University of Tromso Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsThe long-term functional outcome for children treated for low-grade astrocytoma is favourable. However, some patients report neurological complications and learning difficulties, which are unmet in school. Therefore, there is a need to identify those who need more thorough medical and cognitive follow-up programmes including interventions in school.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSION: The use of rodent models of depression, gene analysis of hippocampal tissues of MDD patients and post-mortem studies of brains from MDD patients suggest that astrocytic gap junction dysfunction may be part of MDD etiologies. Chronic antidepressant treatments of rats, rat cultured cortical astrocytes and human astrocytoma cell lines support the hypothesis that the up-regulation of gap junctional coupling between astrocytes could be an underlying mechanism for the therapeutic effect of antidepressants. However, two recent functional studies suggest that connexin43 hemichannel activity is part of several antidepre...
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research
This study was performed to quantify serial changes in lymphocyte subsets in HGA following standard radiation (RT) and temozolomide (TMZ). Adults (KPS  >60, HIV negative) with newly diagnosed HGA scheduled to receive concurrent RT and TMZ and adjuvant TMZ were eligible. Blood was collected before beginning concurrent RT/TMZ and at weeks 6, 10, 18, and 26, and 3 months after completing adjuvant TMZ. Lymphocyte subsets were analyzed by flow cytometry. Twenty patients (70% glioblastoma, median age 53, 50% male, 80% Caucasian) who enrolled from January 2014 to August 2014 were followed until April 2016. Baseline dexa...
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
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