Dissecting an outbreak: A clinico-epidemiological study of Nipah virus infection in Kerala, India, 2018

Conclusion: The rapid spread of infection uncovered the miserable state of health care system in implementing infection control measures. The case fatality and the socio-economic burden warrant developing appropriate treatments, vaccines and diagnostics.
Source: Journal of Global Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research

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The number of disorders associated with congenital or acquired asplenia and functional hyposplenism has increased substantially over the past couple decades. Previously, screening for asplenia and hyposplenism was a barrier to identifying patients at risk. Recent methods for measuring splenic function have emerged as accurate and reliable. Identifying patients prevents overwhelming postsplenectomy infection or invasive pneumococcal disease. Approaches to protect patients with asplenia or hyposplenism include patient education of risks and signs/symptoms of infection, vaccination, and antibiotic prophylaxis. Physicians have...
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Source Type: research
Evaluation of antibodies produced after immunization is central to immune deficiency diagnosis. This includes assessment of responses to routine immunizations as well as to vaccines administered specifically for diagnosis. Here, we present the basic concepts of the humoral immune response and their relevance for vaccine composition and diagnosis of immune deficiency. Current vaccines are discussed, including nonviable protein and glycoprotein vaccines, pure polysaccharide vaccines, polysaccharide –protein conjugate vaccines, and live agent vaccines. Diagnostic and therapeutic applications of vaccine antibody measurem...
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Source Type: research
Authors: Naik R, Peden K Abstract Developing traditional viral vaccines for infectious diseases usually takes years, as these are usually produced either by chemical inactivation of the virus or attenuation of the pathogen, processes that can take considerable time to validate and also require the live pathogen. With the advent of nucleic-acid vaccines (DNA and mRNA), the time to vaccine design and production is considerably shortened, since once the platform has been established, all that is required is the sequence of the antigen gene, its synthesis and insertion into an appropriate expression vector; importantly...
Source: Current Topics in Microbiology and Immunology - Category: Microbiology Tags: Curr Top Microbiol Immunol Source Type: research
Publication date: Available online 9 July 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Pei-Hsuan Tsai, Mao-Song Tsai, Yin-Hsuan Chiang, Chung-Yu Shih, Chia-Ying Liu, Yu-Chung Chuang, Chia-Jui Yang
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
Publication date: Available online 9 July 2020Source: Saudi Journal of Biological SciencesAuthor(s): Mekhled M. Alenazi, Muhammad Shafiq, Abdullah A. Alsadon, Ibrahim M. Alhelal, Abdullah M. Alhamdan, Talaat.H.I. Solieman, Abdullah A. Ibrahim, Mohammd R. Shady, Montasir A.O. Saad
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: Available online 9 July 2020Source: Saudi Journal of Biological SciencesAuthor(s): Seham S. El-Hawary, Mansour Sobeh, Wafaa K. Badr, Mohamed A.O. Abdelfattah, Zeinab Y. Ali, Mona E. El-Tantawy, Mohamed A. Rabeh, Michael Wink
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: Available online 8 July 2020Source: Clinical Epidemiology and Global HealthAuthor(s): Aparup Das
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
Covid-19 outbreak accelerates across Africa; Venezuelan Socialist Party boss also tests positive; Brazilian President Jair Bolsonaro ‘in good health’. Follow the latest updates:South Africa warns of coronavirus ‘storm’ as outbreak accelerates across continentBolivia ’s president and Venezuela’s Socialist party leader test positive for Covid-19WHO says coronavirus pandemic still acceleratingTrudeau and Trump ’s responses see wildly different results1.54amBSTPlans for the fall semester at the University ofCalifornia, Berkeley, are in question after 47 new Covid-19 cases tied to frate...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news UK news US news Australia news Science Infectious diseases Africa Microbiology Medical research Source Type: news
Publication date: Available online 8 July 2020Source: Medicina Intensiva (English Edition)Author(s): A. González-Castro, P. Escudero-Acha, Y. Peñasco, O. Leizaola, V. Martínez de Pinillos Sánchez, A. García de Lorenzo
Source: Medicina Intensiva - Category: Intensive Care Source Type: research
WHO says pandemic is still accelerating; Hundreds of Romanians check themselves out of hospital; Serbia considers new lockdown. This blog is now closedFollow the latest global coronavirus live blog hereWHO says coronavirus pandemic still acceleratingWarning of Covid-19 ‘storm’ as pandemic accelerates across AfricaTrudeau and Trump ’s responses see wildly different results12.39amBSTWe ’ve launched a new blog at the link below – head there for the latest:Related:Coronavirus live news: Bolivia president tests positive amid record rise in South Africa cases12.05amBSTSouth Africa announced Thursday...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news US news Australia news UK news Science Infectious diseases Source Type: news
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