Tolerability and safety of EUS-injected adenovirus-mediated double-suicide gene therapy with chemotherapy in locally advanced pancreatic cancer: Phase I Trial

Locally advanced pancreatic cancer (LAPC) is challenging. Here we aimed to evaluate the tolerability and safety of Ad5-yCD/mutTK(SR39)rep-ADP (Ad5-DS), a replication-competent adenovirus-mediated double-suicide gene therapy in combination with gemcitabine in LAPC patients.

Source: Gastrointestinal Endoscopy - February 17, 2020 Category: Gastroenterology Authors: Jong-chan Lee, Dong Woo Shin, Haeseong Park, Jinkuk Kim, Yuna Youn, Jae Hyeong Kim, Jaihwan Kim, Jin-Hyeok Hwang Source Type: research