Identification of Dysfunctional Gut Microbiota Through Rectal Swab in Patients with Different Severity of Acute Pancreatitis

ConclusionsThe disturbed gut microbiota is different among grades of AP, suggesting their potential role in the progression of disease severity.Graphic AbstractThere was a different microbiota profile in different severity grades.Bacteroides,Escherichis-Shigella, andEnterococcus were dominant gut microbiota species in MAP, MSAP, and SAP, respectively.Finegoldia was the most significantly increased andBlautia the most decreased gut microbiota species in MAP.Anaerococcus was the most significantly increased andEubacterium hallii the most decreased species in MSAP.Enterococcus was the most significantly increased andEubacterium hallii the most decreased species in SAP.Finegoldia,Eubacterium_hallii, andLachnospiraceae were potential diagnostic biomarkers for MAP andEubacterium_hallii andAnaerococcus for MSAP. There was a positive interaction betweenFirmicutes andBacteroidetes in MAP.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research