Using process improvement and systems redesign to improve rheumatology care quality in a safety net clinic.
CONCLUSION: Through an interprofessional approach, we were able to achieve durable improvements in key rheumatology quality measures largely by enhancing workflow, engaging non-physician providers and managing practice variation. PMID: 32062597 [PubMed - as supplied by publisher]
Conclusion: The current study highlighted a distinct pattern and profile of scleritis patients in Bangladesh. PMID: 32130057 [PubMed - as supplied by publisher]
ConclusionThe LTBI developed in 9.4% of the patients. This is higher than what is reported for previous US studies. Screening for LTBI in the US should take into consideration TB prevalence, ethnicity, drug type, and duration of use. For our local population and similar populations, annual screening should be practiced.Key Points• Although patients on TNFα inhibitor (TNFα-I) therapy are at high risk of latent tuberculosis infection (LTBI), few studies report the rate of LTBI in patients living in high prevalence areas of the US.• The rate of LTBI was 9.4% in patients on TNFα-I therapy in Souther...
ConclusionA review of the literature identified only few cases of closed avulsion of FDS tendons nonpathologically. Early diagnosis and intervention can prevent sequel of flexion contracture.
ConclusionOur SLR identified a lack of high-quality evaluations assessing bDMARD sequences, although some improvements were made in the reporting and modelling of patients ’ pathways in studies published after 2010. In order to improve economic evaluations of RA, clear health technology assessment guidance on RA health-related QoL instruments must be provided, and data including long-term disease progression must be made available.
ConclusionGiven the relatively low incidence of immune ‐related AEs and the comparability of clinical outcomes, ICIs can be treatment option of NSCLC patients with special issues.
Abstract Tuberculosis is the most lethal infectious disease globally, but the vast majority of people who are exposed to the primary causative pathogen, Mycobacterium tuberculosis (MTB), do not develop active disease. Most people do, however, show signs of infection that remain throughout their lifetimes. In this review, we develop of framework that describes several possible transitions from pathogen exposure to TB disease and reflect on the genetics studies to address many of these. The evidence strongly supports a human genetic component for both infection and active disease, but many of the existing studies, i...
One of the most important messages from the recent review is that diagnostic difficulty can occur as a result of clinical presentations of extrapulmonary tuberculosis that overlap with other conditions . Conditions which can overlap with extrapulmonary manifestations of tuberculosis include extrapulmonary manifestations of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Immunoglobulin G4-Related Disease (IgG4-RD) and cryptococcal infection. In each of these disorders the extrapulmonary complications which occur may be indistinguishable from the extrapulmonary manifestations of tuberculosis.
We thank Dr. Jolobe for his insightful comments regarding our review “Tuberculosis: a focused review for the emergency medicine clinician” [1,2]. Dr. Jolobe highlighted several conditions that present similarly to tuberculosis (TB), including pleural effusion in a patient with previously diagnosed rheumatoid arthritis and systemic lupus erythematosus, pericardial effusion in a patient with previously diagnosed rheumatoid arthritis and systemic lupus erythematosus, immunoglobulin G4-related pleuropulmonary disease and tuberculous pleurisy, and disseminated tuberculosis in a patient with cryptococcal meningitis .
Conclusions: Clinicians may encounter difficulties when treating PTB in patients with RD. Despite the favorable long-term outcomes of RD patients, the outcomes of individual patients such as those with systemic lupus erythematosus (SLE) should be interpreted with caution during post-therapy follow-up. PMID: 31903246 [PubMed]
We describe a single institute review of 78 such cases that resemble and mimic Pott's spine on MRI. The cases being: (n = 15) pyogenic spondylitis, (n = 1) brucellar spondylodiscitis, (n = 12) rheumatoid arthritis, (n = 12) metastases, (n = 8) lymphoma, (n = 5) post-trauma fractures, (n = 10) degenerative disc disease, (n = 2) Baastrup's disease, (n = 9) osteoporotic fracture, (n = 3) spinal neuropathic arthritis, and (n = 1) case of Rosai–Dorfman disease. The clinical and radiological findings of all these cases were correlated with lab findings and histopathology ...