Autophagy During Left Ventricular Redilation After Ventriculoplasty: Insights from a Rat Model of Ischemic Cardiomyopathy

Myocardial autophagy has been recognized as an important factor in heart failure. It is not known whether changes in ventricular geometry by left ventriculoplasty influence autophagy in ischemic cardiomyopathy. We hypothesized that myocardial autophagy plays an important role in left ventricular (LV) redilation after ventriculoplasty.

Source: The Journal of Thoracic and Cardiovascular Surgery - February 17, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Satoshi Sugimoto, Yasushige Shingu, Torsten Doenst, Tomoji Yamakawa, Hidetsugu Asai, Satoru Wakasa, Yoshiro Matsui Source Type: research