The impact of ethnicity on the clinical presentations of spinocerebellar ataxia type 3

For a variety of sporadic neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis, it is well-established that ethnicity do affect the disease phenotypes. However, how the ethnicity could contribute to the clinical symptoms and disease progressions in monogenetic disorders, such as spinocerebellar ataxia type 3 (SCA3), remains less studied.

Source: Parkinsonism and Related Disorders - February 17, 2020 Category: Neurology Authors: Shi-Rui Gan, Karla P. Figueroa, Hao-Ling Xu, Susan Perlman, George Wilmot, Christopher M. Gomez, Jeremy Schmahmann, Henry Paulson, Vikram G. Shakkottai, Sarah H. Ying, Theresa Zesiewicz, Khalaf Bushara, Michael D. Geschwind, Guangbin Xia, S.H. Subramony, Source Type: research