GSE145412 Evaluation of transcriptomic regulations behind metabolic syndrome in obese and lean subjects

Contributors : Paczkowska-Abdulsalam Magdalena ; Magdalena Niemira ; Agnieszka Bielska ; Anna Sza łkowska ; Edyta Adamska-Patruno ; Adam KrętowskiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe study aimed to investigate molecular signatures in peripheral blood of individuals affected by metabolic syndrome (MetS) and different degrees of obesity. Metabolic health of 1204 individuals was assessed, and 32 subjects were recruited to four study groups: MetS lean, MetS obese, “healthy obese” and healthy lean. Whole-blood transcriptome next generation sequencing with functional data analysis were carried out. MetS obese and MetS lean study participants showed the upregulation of genes involved in inflammation and coagulation processes: granulocyte adhesion and diapede sis (P
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research