A New Page in Life
By Anna-Maija Mattila-Litvak, Supervisory Development Outreach and Communications Officer Anita Nakazibwe holds her daughter Emmanuela. While mom is HIV-positive, the toddler remains HIV-negative —a fact that brings Anita great joy. Photo by Anna-Maija Mattila-Litvak, USAID/Uganda.February 17, 2020“My first treatment was a smile!” says Anita Nakazibwe about the welcome she got when she first came to Moroto Regional Referral Hospital in eastern Uganda. Anita holds her year-and-a-half-old baby girl Emmanuela in her arms and is beaming. She gave birth at the hospital to a healthy baby, although she herself is HIV-positive.Several years earlier, however, life seemed to come to a stop for Anita.“It was in 2011, when I gave birth to my first child. After a year, I got pregnant again and miscarried and the doctors were trying to find out the reason for it. They did an HIV test and it was positive. Telling my husband was really hard,” recalls Anita solemnly.“Fortunately he has been so supportive and good to me,” she says of her husband, who is HIV-negative.“Then, when my first daughter got sick and tested HIV-positive, it was devastating,” she said. After a few years, Anita and her husband wanted to have another child, but Anita was afraid to get pregnant again.
Perinatal antiretroviral intensification may prevent intrapartum transmission of HIV in women who start combination antiretroviral therapy (cART) late in pregnancy, new research suggests.Reuters Health Information
ConclusionsIn this study, we found that a substantial portion of peripartum women moved within the country around the time of delivery and experienced a significantly higher risk of mortality. Despite the scale-up of universal ART and declining trends in maternal mortality, there is an urgent need to derive a greater understanding of the mechanisms underlying this finding and to develop targeted interventions for mobile HIV-positive peripartum women.
Conclusion: Availability and accessibility of PMTCT programme services are still problematic. The study has the potential to inform development of strategies that may facilitate access to care for PMTCT programme clients. PMID: 32200723 [PubMed - in process]
Authors: Mathad JS, LaCourse SM, Gupta A PMID: 32202066 [PubMed - in process]
CONCLUSIONS: Experiences from the PROMISE study illustrate the challenges of enrolling in longer term studies in the setting of rapidly evolving prevention and treatment standards priorities. The lessons learned will help the community, site investigators, and study coordinators in the design and implementation of future clinical trials. PMID: 32191142 [PubMed - as supplied by publisher]
Objective: To investigate factors contributing to preterm birth (PTB), including cART use and clinical and social determinants of health, in women living with HIV (WLWH) from British Columbia, Canada. Design: Retrospective observational cohort. Methods: We investigated the effect of cART use and other clinical and demographic factors on spontaneous PTB (sPTB) rates (
Objectives: Measuring retention is critical for antiretroviral therapy (ART) management and program monitoring; however, many definitions and data sources, usually from single health facilities, are used. We used routine electronic data, linked across facilities, to examine the impact of definitions and data sources on retention estimates among women in Cape Town, South Africa. Design: Retrospective cohort study. Methods: We compiled routine electronic laboratory, pharmacy and clinic visit data for 617 women who started ART during pregnancy (2013–2014) and estimated 24-month retention using different definiti...
Conclusion: Substantial HIV incidence among pregnant and breast-feeding women in SSA, even in the current era of combination HIV prevention and treatment, underscores the need for prevention tailored to high-risk pregnant and breast-feeding women.