A New Page in Life

By Anna-Maija Mattila-Litvak, Supervisory Development Outreach and Communications Officer Anita Nakazibwe holds her daughter Emmanuela. While mom is HIV-positive, the toddler remains HIV-negative —a fact that brings Anita great joy. Photo by Anna-Maija Mattila-Litvak, USAID/Uganda.February 17, 2020“My first treatment was a smile!” says Anita Nakazibwe about the welcome she got when she first came to Moroto Regional Referral Hospital in eastern Uganda. Anita holds her year-and-a-half-old baby girl Emmanuela in her arms and is beaming. She gave birth at the hospital to a healthy baby, although she herself is HIV-positive.Several years earlier, however, life seemed to come to a stop for Anita.“It was in 2011, when I gave birth to my first child. After a year, I got pregnant again and miscarried and the doctors were trying to find out the reason for it. They did an HIV test and it was positive. Telling my husband was really hard,” recalls Anita solemnly.“Fortunately he has been so supportive and good to me,” she says of her husband, who is HIV-negative.“Then, when my first daughter got sick and tested HIV-positive, it was devastating,” she said. After a few years, Anita and her husband wanted to have another child, but Anita was afraid to get pregnant again.
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: HIV & AIDS Maternal, Newborn, Child Health Nurses Source Type: news

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Condition:   COVID-19 Intervention:   Drug: Remdesivir Sponsor:   International Maternal Pediatric Adolescent AIDS Clinical Trials Group Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study will test MME against treatment as usual (TAU) among pregnant mothers diagnosed with HIV and their infants. Outcomes will be assessed during pregnancy and 16  weeks postpartum. Women who meet eligibility criteria are assigned to MME or TAU. Women assigned to MME are grouped with others with similar estimated delivery dates, completing up to eight intervention group sessions scheduled before week 36 of their pregnancies. Primary outcomes among mothers in clude (i) reducing self-stigma, which is hypothesized to mediate improvements in (ii) psychological outcomes (quality of life, depression and social functio...
Source: Trials - Category: Research Source Type: clinical trials
CONCLUSIONS: Protecting pregnant and breastfeeding women, infants, children and adolescents from acquiring SARS-CoV-2 while sustaining essential HIV services is an immense global health challenge. Tailored, family friendly programme adaptations for case-finding, ART delivery and viral load monitoring for these populations have the potential to limit SARS-CoV-2 transmission while ensuring the continuity of life-saving HIV case identification and treatment efforts. PMID: 32996705 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
[The Conversation Africa] There are more than 85,000 children living with HIV in Zambia. The primary source of infection is from mother to child during pregnancy, childbirth or breastfeeding. Antiretroviral therapy (ART) is an effective strategy to eliminate these new infections. But it only works if women take their medications consistently.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
h W Abstract Tetra-amelia is extremely rare with an incidence of 2.4 per 10,000,000 births. It describes the absence of all 4 outer extremities and can be associated with other malformations. The boy presented here was diagnosed at 22 1/7 weeks of gestation by sonography in 2D and 3D mode. The parents decided to continue the pregnancy; vaginal birth occurred after external rotation at 38 1/7 weeks of pregnancy. Postnatally, surgical closure of a cleft of the soft palate was performed. External abnormalities manifested themselves increasingly in the area of the spine and the face. The anatomically limited psychomot...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - Category: Perinatology & Neonatology Authors: Tags: Z Geburtshilfe Neonatol Source Type: research
Authors: Khan S, Spiegelman D, Walsh F, Mazibuko S, Pasipamire M, Chai B, Reis R, Mlambo K, Delva W, Khumalo G, Zwane M, Fleming Y, Mafara E, Hettema A, Lejeune C, Chao A, Bärnighausen T, Okello V Abstract INTRODUCTION: The WHO recommends antiretroviral treatment (ART) for all HIV-positive patients regardless of CD4 count or disease stage, referred to as "Early Access to ART for All" (EAAA). The health systems effects of EAAA implementation are unknown. This trial was implemented in a government-managed public health system with the aim to examine the "real world" impact of EAAA on care ret...
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: HIV infection that has been treated does not appear to be an independent risk factor for fetal growth restriction or preterm delivery in an SA population. PMID: 32880562 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
[The Conversation Africa] The COVID-19 pandemic tends to conceal other important health issues. One of these is the global target for reducing HIV infections and increasing access to treatment. Progress is well under way. In 2019, 67% of those living with HIV were receiving antiretroviral therapy (ART), and 85% of pregnant women with HIV were receiving medication to prevent transmission to their babies.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
Objective: To evaluate the relationship between cervical cytokine/chemokine concentrations and HIV-1 acquisition in peripartum Kenyan women. Design: Nested case–control study. Methods: Women participating in a prospective study of peripartum HIV acquisition in Kenya (the Mama Salama Study), were tested for HIV-1 at 1–3 month intervals during pregnancy and through 9 months postpartum. Cases positive for HIV-1 RNA during follow-up (N = 14), were matched 3 : 1 with HIV-negative controls (N = 42) based on age, marital status, partner HIV-1 status, transactional sex, and timing of cervical swab c...
Source: AIDS - Category: Infectious Diseases Tags: BASIC SCIENCE Source Type: research
AbstractDiscussing reproductive plans with healthcare providers by women living with HIV (WLHIV) can assist in promoting safe reproductive health practices, but little research has been undertaken in this area. A cross-sectional survey was conducted in western Ethiopia in 2018 among 475 sexually active WLHIV. One hundred and twenty seven (26.8%) participants reported becoming pregnant in the last 5  years after being aware of their HIV-positive status; 33.6% reported their intention to have children in the future, and 26.9% were ambivalent about having children. WLHIV who reported general and personalized discuss...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
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