Gut Bacterial Metabolite Urolithin A Decreases Actin Polymerization and Migration in Cancer Cells

ConclusionUA leads to disruption of Rac1 and Pak1 activity with subsequent actin depolymerization and migration. Thus, use of dietary UA in cancer prevention or as adjuvant therapy is promising.

Source: Molecular Nutrition and Food Research - February 17, 2020 Category: Food Science Authors: Md Alauddin, Toshiyuki Okumura, Janet Rajaxavier, Shayan Khozooei, Simone P öschel, Satoru Takeda, Yogesh Singh, Sara Y Brucker, Diethelm Wallwiener, André Koch, Madhuri S Salker Tags: Research Article Source Type: research