Impact of Sevoflurane Versus Propofol Anesthesia on Post-Operative Cognitive Dysfunction in Elderly Cancer Patients: A Double-Blinded Randomized Controlled Trial.

CONCLUSIONS Sevoflurane-based anesthesia did not increase the incidence of POCD compared to propofol-based anesthesia at 7 days or 3 months post-operation or impact short-term post-operative prognosis. PMID: 32060257 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research

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AbstractOpioid overdose accounted for more than 47,000 deaths in the United States in 2018. The risk of new persistent opioid use following breast cancer surgery is significant, with up to 10% of patients continuing to fill opioid prescriptions one year after surgery. Over prescription of opioids is far too common. A recent study suggested that up to 80% of patients receiving a prescription for opioids post-operatively do not need them (either do not fill the prescription or do not use the medication). In order to address this important issue, The American Society of Breast Surgeons empaneled an inter-disciplinary committe...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSION Both MICT and HIIT enhanced pre-operative functional capacity. TRIAL REGISTRATION Identifier: NCT03361150.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Regional anaesthesia Source Type: research
Authors: Di Marzo F, Fiori E, Sartelli M, Cennamo R, Coccolini F, Catena F, Calabretto M, Riveros Cabral RJ, Lombardi M, Baiocchi GL, Cardi M, Cusi MG, Cardi M Abstract The SARS-CoV-2 pandemic has already reached 3,207,248 patients with more than 225,000 deaths all over the world. Colorectal cancer is the third most diagnosed cancer worldwide, and the healthcare system is struggling to manage daily activities for elective cancer surgery. This review integrates clinical, microbiological, architectural and surgical aspects to develop indications on strategies to manage colorectal cancer patients and ensure safety dur...
Source: New Microbiologica - Category: Microbiology Tags: New Microbiol Source Type: research
ConclusionPOI is a common complication after hysterectomy. This study identified risk factors of POI specifically for gynecologic patients. Patients exposed to these factors should be monitored closely for the development POI.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
AbstractBackgroundThe proposed difficulty scoring system (DSS) may aid in preoperative planning for laparoscopic total mesorectal excision (L-TME) for rectal cancer.MethodsFifty-three patients [28 males; 59.0 (31.0 –88.0) years of age] treated for rectal cancer at our institution from 2/2011–5/2018 were identified. “Difficult operation” (DO) was defined as the presence of ≥3 factors: operative time ≥320 min, estimated blood loss>250  ml, intraoperative complications, conversion to laparotomy,>2 stapler applications, incomplete TME quality, and/or subjective perceived diffi...
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
ConclusionsThe study results suggest that patients with high risk for OSA have a tendency to develop postoperative wound complications after breast cancer surgery. This study lays groundwork for further scrutiny using more robust methodology.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
ConclusionsNovel nano-enhanced radiotherapy with gadolinium-containing nanoparticles is ideally suited for implementation on an MRI-linac, allowing a workflow with time-of-treatment imaging. Live irradiations using this treatment workflow, carried out for the first time at the Australian MRI-linac, confirm the safety and feasibility of performing MRI-guided radiotherapy with AGuIX® nanoparticles. Follow-up studies are needed to demonstrate on an MRI-linac the radiation enhancement effects previously shown with conventional radiotherapy.
Source: Cancer Nanotechnology - Category: Cancer & Oncology Source Type: research
This study aimed to compare the effects of BIS-guided individualized anesthesia with standard general anesthesia on emergence and delirium after esophagectomy. MATERIAL AND METHODS Data on 161 elderly patients undergoing esophagectomy for cancer were retrospectively obtained from electronic medical records. We performed propensity score matching analysis between patients receiving individualized anesthesia (BIS value maintained at about 10 less than the value at LOC) and those receiving standard anesthesia (BIS value maintained at 40-60). In addition, we conducted univariate and multivariate logistic -analyses in the entir...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
In this report, both patients had lung mass accompanied by cough that lasted for>2 weeks, and were admitted to hospital for further diagnosis and treatment to clarify the nature of the mass. To make a definite diagnosis, EBUS-TBNA examination was performed under general anesthesia. Both patients had no salient past history. Diagnosis: Case 1 was diagnosed as tumor or pneumonia based on the right lung shadow. Case 2 was diagnosed with squamous cell carcinoma of the right lung with right hilar lymph node metastasis. The diagnostic results of both patients were based on pathological examination of tissues obtained by EB...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Digital media&downloads Pain Relief Caused by SARS-CoV-2 Infection May Help Explain COVID-19 Spread New research shows SARS-CoV-2 promotes pain relief when it infects cells through a common protein receptor, neuropilin-1. The finding gives scientists a novel target for non-opioid pain therapeutics, while also offering an explanation for the unrelenting spread of COVID-19. Stacy Pigott Today University of Arizona Health SciencesKhanna_Raj_klh3067.jpg Doctoral student Lisa Boinon prepares buffers while Rajesh Khanna looks on. (Photo: Kris Hanning/University of Arizona Health Sciences)HealthCollege of Medicine - Tuc...
Source: The University of Arizona: Health - Category: Universities & Medical Training Authors: Source Type: research
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