Integrative Clustering Reveals a Novel Subtype of Soft Tissue Sarcoma With Poor Prognosis

ConclusionIntegrative clustering analysis revealed that the STSs could be clustered into three sub-clusters. The ceRNA network, especially the subnetwork LncRNA (KCNQ1OT1)-miRNA (has-miR-29c-3p)-mRNA (JARID2, CDK8, DNMT3A, TET1) was a promising therapeutic target for the STS sub-cluster associated with a poor prognosis.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research