Clinical relevance of total choline (tCho) quantification in suspicious lesions on multiparametric breast MRI

ConclusionQuantitative tCho evaluation from1H-MRS allowed diagnose malignancy and lymph node status in breast lesions suspicious on multiparametric breast MRI. tCho therefore demonstrated the potential to downgrade suspicious mpMRI lesions and stratify the risk of lymph node metastases for improved patient management.Key Points• Quantitative tCho evaluation can distinguish benign from malignant breast lesions suspicious after multiparametric MRI assessment.• Quantitative tCho levels are associated with lymph node status in breast cancer.• Quantitative tCho levels are higher in hormonal receptor positive compared to hormonal receptor negative lesions.

http://link.springer.com/10.1007/s00330-020-06678-z

Source: European Radiology - February 16, 2020 Category: Radiology Source Type: research