Do detergents cause childhood asthma? Cases of the disease rise 37% in 'extra clean' homes
Household cleaning products could be linked to childhood asthma, research published today suggests. More than five million people in Britain have asthma, including 1.1million children.
Publication date: Available online 5 April 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Schleich Florence, Vaia Elleni-Sofia, Pilette Charles, Vandenplas Olivier, Halloy Jean-Luc, Michils Alain, Peche Rudy, Hanon Shane, Louis Renaud, Michel Olivier
The READY study evaluated the effect and the cost benefits of a community health worker-led home intervention on improving outcomes for Medicaid-enrolled children with uncontrolled asthma.Preventing Chronic Disease
This observational study examines the pathophysiological changes in the small airways associated with using a fine particle (PM2.5) –removing device in bedrooms of children with asthma.
npj Primary Care Respiratory Medicine, Published online: 06 April 2020; doi:10.1038/s41533-020-0170-6Asthma phenotypes in primary care
npj Primary Care Respiratory Medicine, Published online: 06 April 2020; doi:10.1038/s41533-020-0168-0Data-driven questionnaire-based cluster analysis of asthma in Swedish adults
Contributors : WeiQi Zhai ; QingZhu SunSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensOur previous studies proved that both epithelial inflammation and sub-epithelial remodeling were linked to deregulated PRMT1 expression in asthma patients. This sncRNA-seq data from the BEAS-2B cell line after over-expressed PRMT1 for 24h.
In this study, we analyzed the immunoexpression of cluster of differentiation (CD) 20, CD8, CD138 and eosinophil major basic protein (MBP) in 24 cases of CR in adolescents, in eight of them existing the association of asthma. Symptoms of CR and allergic status, as well as histopathological changes specific to a persistent inflammation, were identified in this study. The CD20∕CD8 immunophenotype was more specific for CR, while the CD138∕eosinophil MBP immunophenotype was specific for asthma-associated chronic rhinitis (AACR). The negative linear distribution of lymphocyte elements compared to plasmocytes and eosinophils...
CONCLUSION: Only Portugal, Brazil and Mozambique adopted asthma integrated disease management as the main form of asthma management and control. The programs developed by these countries can constitute a model for asthma integrated disease management in the other countries under study. PMID: 32238241 [PubMed - in process]
Authors: Seyedrezazadeh E, Ansarin K, Sharifi A, Jafari Rouhi AH, Gilani N, Aftabi Y, Khalili M, Najmi M Abstract Objective: The work productivity and activity impairment (WPAI) questionnaire is a fine linguistic validated tool to measure work productivity and activity impairment. Considering its capability, this study aimed to evaluate the validity of the Persian version of WPAI-AQ in asthmatics.Methods: The standard forward-backward process was used to translate the English version of WPAI-AQ into Persian. The convergent validity and responsiveness were evaluated by analysing the correlations between the Persian ...
Authors: Kotsiou OS, Gourgoulianis KI, Daniil Z Abstract The confessional aspect of seeing behind the scenes in severe asthma by clinical severe asthma phenotyping could improve treatment outcomes, quality of life, morbidity, and mortality of asthma patients. The growing availability of rich clinical data could provide opportunities to address a broad range of real-world questions regarding clinical phenotyping and effective therapeutic approach of severe asthma. Accordingly, in this Letter to the Editor, we provide data relevant to constructing the clinical profile of a Greek severe asthma patient cohort who recei...