Altered lateral geniculate nucleus functional connectivity in migraine without aura: a resting-state functional MRI study

ConclusionsPhotophobia in MwoA could be mediated by abnormal resting state functional connectivity in visual processing regions, the pain perception regulatory network and emotion regulation network. This result is valuable to further understanding about the clinical manifestation and pathogenesis of migraine.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research

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Conclusions: RC is reported to be effective in treating a variety of diseases. Current pharmacological studies on RC mainly focus on the nervous, circulatory, digestive, and endocrine systems, as well as drug withdrawal. Although experimental data support the beneficial effects of this drug, its physiological activity remains a concern. Nonetheless, this review provides a foundation for future research. PMID: 32223481 [PubMed - in process]
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
AbstractPurpose of ReviewEffective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic. Persistent postsurgical pain (PPP) has an incidence of up to 30 –50% and has negative outcome of quality of life and negative burden on individuals, family, and society. The 2016 American Society of Anesthesiologists (ASA) guidelines states that enhanced recovery after surgery (ERAS) forms an integral part of Perioperative Surgical Home (PSH) and is now recomm ended to use a multimodal opioid-sparing approach for management of postoperative...
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
Abstract Most frequent headaches are typically migraine or tension-type headaches and are often exacerbated by medication overuse. Repeated headaches can induce central sensitization and transformation to chronic headaches that are intractable, are difficult to treat, and cause significant morbidity and costs. A complete history is essential to identify the most likely headache type, indications of serious secondary headaches, and significant comorbidities. A headache diary can document headache frequency, symptoms, initiating and exacerbating conditions, and treatment response over time. Neurologic assessment and...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Conclusion Surgical decompression of the optic canal and orbital contents for tumor related sphenoid wing hyperostosis should be strongly considered, despite an extended duration of visual change and loss. This case report shows that vision can be significantly restored even after symptoms have been present for greater than 6 months. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Journal of Neurological Surgery Reports - Category: Neurosurgery Authors: Tags: Case Report Source Type: research
(HAMBURG, Pa.) — The spring breezes of 2020 are carrying more than just tree pollen. There’s a whiff of paranoia in the air. For millions of seasonal allergy sufferers, the annual onset of watery eyes and scratchy throats is bumping up against the global spread of a new virus that produces its own constellation of respiratory symptoms. Forecasters are predicting a brutal spring allergy season for swaths of the U.S. at the same time that COVID-19 cases are rising dramatically. That’s causing angst for people who never have had to particularly worry about their hay fever, other than to stock up on antihista...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 News Desk wire Source Type: news
“Headaches aren’t welcome here” — that’s the sign you have hanging on your brain’s front door, but the pain is barging right in. You can chalk it up to stress from world events or something you ate or drank, and you might be right. But there are a number of common triggers for migraines, tension headaches, or cluster headaches. The faster you identify them, the quicker you can boot headache pain off the property. What are the triggers for your headaches? Take note of your circumstances when a headache starts. Keep a diary to track the day, time, symptoms, and circumstances surrounding th...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Headache Health Men's Health Women's Health Source Type: blogs
ConclusionThe posterior hypothalamus might thus be hyperexcitable in cluster headache patients outside the bout while excitability to external nociceptive stimuli decreases during in bout periods, probably due to frequent hypothalamic activation and possible neurotransmitter exhaustion during cluster attacks.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
Chronic tension type headache (CTTH) is one of the common cause of hospital visits among adolescents and adults. Chronic tension type headache produces pain, sleep disturbances, and disability among patients leading to a poor quality of life. Knowledge pattern of headache and various associated factors will aid appropriate management.
Source: Pain Management Nursing - Category: Nursing Authors: Tags: Original Article Source Type: research
This study investigates the types and degrees of physical and psychological discomfort experienced by hematopoietic stem cell donors before, during, and after the donation process in order to provide helpful information for developing education programs that can help donors to cope with their discomforts. One hundred and thirty-one individuals who donated hematopoietic stem cells from 2017 to 2019 were asked to self-report the types and degrees of physical and psychological discomfort they felt in the process, and the results were analyzed using SPSS. All participants donated peripheral blood stem cells; the most commonly ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
AbstractMigraine headache is a common, chronic, debilitating disease with a complex etiology. Current therapy for migraine headache comprises either treatments targeting acute migraine pain or prophylactic therapy aimed at increasing the length of time between migraine episodes. Recent evidence suggests that calcium gene-related peptide (CGRP) is a critical component in the pathogenesis of migraines. Fremanezumab, a monoclonal antibody against CGRP, was recently approved by the Food and Drug Administration (FDA) after multiple studies showed that it was well-tolerated, safe, and effective in the treatment of migraines. Fur...
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
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