Paradigm shift in the management of bile duct strictures complicating living donor liver transplantation

ConclusionA paradigm shift in the approach to management of biliary strictures complicating LDLT is proposed whereby a multidimensional definition of FSO can help in reliable patient selection for endotherapy and improve patient outcome as a whole.
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research

Related Links:

We report the case of a 53-year-old man with portal vein LMS presenting as a hilar tumor and causing cholestasis. The tumor measured 10 cm and was responsible for right portal vein thrombosis and compression of the biliary convergence. A right hepatectomy with hilar en bloc resection was performed with portal vein and biliary reconstruction. Pathology confirmed the complete resection of a well-differentiated leiomyosarcoma of the portal vein. The postoperative outcome was uneventful and the patient received no adjuvant treatment. Six months after the procedure, the patient is doing well with a normal quality of life and wi...
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Conclusion We conclude that clinically identifiable CT is rare in the neonatal population. Furthermore, catheter-specific characteristics are predictive for CT and require further investigation. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
A term male infant presented on day three of life with a 12-hour history of poor feeding, lethargy, jaundice and hypothermia (35.8 °C). Pregnancy was complicated by cholestasis; however, birth history was uneventful. Examination was significant for a non-dysmorphic intubated male infant with minimal response to painful stimuli. Neuroimaging identified bilateral intraventricular hemorrhage and sagittal venous thrombosis.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Short Communication Source Type: research
This term male infant presented on day three of life with a 12-hour history of poor feeding, lethargy, jaundice, and hypothermia (35.8 °C). Pregnancy was complicated by cholestasis; however, birth history was uneventful. Examination was significant for a non-dysmorphic intubated male infant with minimal response to painful stimuli. Neuroimaging identified bilateral intraventricular hemorrhage and sagittal venous thrombosis.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Clinical Letter Source Type: research
Conclusions Taken together, further preclinical studies are required to confirm the pharmacological properties of α-asarone against depression, anxiety, Parkinson's disease, psychosis, drug dependence, pain, inflammation, cholestasis and thrombosis. Besides, the anticancer effect of β-asarone should be further studied in different types of cancers using in vivo models. Moreover, further dose-dependent in vivo studies are required to confirm the toxicity of α- and β-asarone. Overall, this extensive review provides a detailed information on the preclinical pharmacological and toxicological activities of...
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Conclusions: Cholestatic liver disease induces multiple platelet activation defects and impairs thrombus formation responsible for bleeding complications at least in mice.Cell Physiol Biochem 2017;41:2133 –2149
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Conclusions Taken together, further preclinical studies are required to confirm the pharmacological properties of α-asarone against depression, anxiety, Parkinson's disease, psychosis, drug dependence, pain, inflammation, cholestasis and thrombosis. Besides, the anticancer effect of β-asarone should be further studied in different types of cancers using in vivo models. Moreover, further dose-dependent in vivo studies are required to confirm the toxicity of α- and β-asarone. Overall, this extensive review provides a detailed information on the preclinical pharmacological and toxicological activities of...
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
α-granule biogenesis: from disease to discovery. Platelets. 2017 Mar;28(2):147-154 Authors: Chen CH, Lo RW, Urban D, Pluthero FG, Kahr WH Abstract Platelets are critical to hemostasis and thrombosis. Upon detecting injury, platelets show a range of responses including the release of protein cargo from α-granules. This cargo is synthesized by platelet precursor megakaryocytes or endocytosed by megakaryocytes and/or platelets. Insights into α-granule biogenesis have come from studies of hereditary conditions where these granules are immature, deficient or absent. Studies of Arthrogrypos...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
Conclusion Co-existence of sarcoidosis, CD and APS is extremely rare. APS should be recognized as an accompanying disorder of sarcoidosis and antiphospholipids measured especially when there is a history of thrombosis or miscarriages. CD should not be overlooked in association to sarcoidosis, given the shared immunological and genetic background, even in the absence of a typical presentation of the disease.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
This article is protected by copyright. All rights reserved.
Source: American Journal of Hematology - Category: Hematology Authors: Tags: 40th Anniversary Issue Source Type: research
More News: Bile | Bilirubin | Blood Transusion | Cholestasis | Gastroenterology | India Health | Liver | Liver Transplant | Thrombosis | Transplants | Urology & Nephrology