The attenuating effect of curcumin on morphine dependence in rats: the involvement of spinal ...

Conclusion: In conclusion, the results of this study demonstrated that curcumin exerts a remarkable reducing effect on morphine dependence in rats. The findings showed that the therapeutic effect of curcumin on morphine dependence is mediated through the suppression of activated microglial cells and reduction of inflammatory cytokines levels in the spinal cord.
Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research