Fibrosis-4 index reflects right-sided filling pressure in patients with heart failure

AbstractThe fibrosis-4 index (FIB-4 index) is a marker of liver fibrosis. It has been reported that the FIB-4 index in compensated phase is associated with estimated right-sided filling pressure and poor prognosis in patients with heart failure. However, the relationship with invasively obtained right-sided cardiac pressures has been unclear. Hemodynamic status was evaluated by right heart catheterization in 189 heart failure patients who were in a clinically compensated phase between January 2015 and September 2017. Patients were assigned to two groups based on a median FIB-4 index of 2.15, then hemodynamic parameters and event rates were compared. Endpoint was defined as a composite of all-cause death, readmission for heart failure, or left ventricular-assist device implantation. Then, we also investigated correlations between the FIB-4 index and clinical factors, including hemodynamic parameters. Patients with a high FIB-4 index were significantly older (76 [IQR, 63 –80] vs. 65 [IQR, 56–74] years,P 
Source: Heart and Vessels - Category: Cardiology Source Type: research

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AbstractAimsThe aim of this study is to evaluate the contemporary use of a pulmonary artery catheter (PAC) in acute myocardial infarction ‐cardiogenic shock (AMI‐CS).Methods and resultsA retrospective cohort of AMI ‐CS admissions using the National Inpatient Sample (2000–2014) was identified. Admissions with concomitant cardiac surgery or non‐AMI aetiology for cardiogenic shock were excluded. The outcomes of interest were in‐hospital mortality, resource utilization, and temporal trends in cohorts with and without PAC use. In the non‐PAC cohort, the use and outcomes of right heart catheterization was evalu...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
The objective of this study was to assess whether CPET metrics could reliably predict hemodynamic pressures.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (565) Source Type: research
Left ventricular assist devices (LVAD) are utilized in patients diagnosed with advanced heart failure. Right ventricular (RV) failure can affect up to 20% of patients undergoing LVAD implantation.In this case study, we evaluated perioperative RV performance with simultaneous use of Swan-Ganz catheterization and high-fidelity conductance catheters to generate real time RV pressure- volume (PV) loops.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (844) Source Type: research
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Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
Conditions:   Chronic Heart Failure;   Non-ischemic Cardiomyopathy;   Non-ischemic Dilated Cardiomyopathy Interventions:   Procedure: Cardiac catheterization;   Biological: Intracoronary administration of the umbilical cord-derived mesenchymal stromal cells Sponsors:   The Research-Clinical Center for Cardiac Surgery and Transplantology LLP;   State-Financed Health Facility " Samara Regional Medical Center Dinasty " Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionApproximately 1 in 6 patients were readmitted after VT ablation, with paroxysmal VT being the most common cause of the readmission. A complication rate of 8.2% was noted. We also identified a predictive model for increased risk of readmission, complication, and factors influencing the cost of care which can be utilized to improve the outcomes related to VT ablation.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: ELECTROPHYSIOLOGY Source Type: research
AbstractMyocardial infection by Epstein –Barr virus (EBV) may manifest with inflammatory cardiomyopathy, coronary syndrome X, and rarely with infarct‐like myocarditis. The aim of the report is to describe a case of myocardial EBV infection causing acute myocarditis with heart failure, necrotizing coronary vasculitis, and multiple left ventricular (LV) aneurysms. A 67‐year‐old woman presented with fever, chest pain, and heart failure. She underwent non‐invasive cardiac studies including electrocardiography, 2D‐echocardiography, cardiac magnetic resonance, hematochemical exams with Troponin T determination, a...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Case Report Source Type: research
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Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Study Design Source Type: research
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