KTHV's Ed Buckner Takes Leave
KTHV chief meteorologist Ed Buckner announced in a Facebook post he's taking a leave of absence to heal from complications of Tourette syndrome.
Tourette's disorder (TD) is one of the five American Psychiatric Association's 2013 Diagnostic and Statistical Manual of Mental Disorders (DSM-5) classifications of tic disorders. Eponymously linked with the noted 19th century French physician, Gilles de l...
Tourette syndrome (TS) is a neurodevelopmental condition characterized by the presence of multiple tics. In addition to common behavioral co-morbidities such as obsessive-compulsive disorder and attention-deficit and hyperactivity disorder, patients with T...
Conclusion: This study suggests that IMMP2L deletions do not lead to a substantial general mitochondrial dysfunction in GTS fibroblasts. Assessing a large cohort of controls and patients of similar age and gender would possibly reveal small differences in mitochondrial function. However, it is possible that IMMP2L variants affect mitochondrial function during specific instances of stress stimuli or in brain regions suggested to be affected in GTS.
Conclusions: Preliminary literature suggests that FMT may be a promising treatment option for several neurological disorders. However, available evidence is still scanty and some contrasting results were observed. A limited number of studies in humans have been performed or are ongoing, while for some disorders only animal experiments have been conducted. Large double-blinded randomized controlled trials are needed to further elucidate the effect of FMT in neurological disorders.
Publication date: Available online 20 March 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Megan Stafford, Andrea E. Cavanna
(Goethe University Frankfurt) A particular neuronal circuit in the brains of bats controls their vocalisations. This was recently discovered by biologists at Goethe University Frankfurt. Based on the rhythm with which the circuit oscillated, the Frankfurt researchers were able to predict the kind of sounds the bats were about to make. These research results could contribute to a better understanding of human diseases in which language is impaired such as Parkinson's or Tourette syndrome.
Future Neurology, Ahead of Print.
AbstractPurpose of reviewThis review presents a critical appraisal of current therapeutic strategies for tics in patients with Tourette syndrome (TS) and other chronic tic disorders. We discuss the most recent evidence to support behavioural/psychosocial, pharmacological and surgical interventions in patients with tics and summarize existing recommendations about treatment selection. We also indicate the main knowledge gaps regarding efficacy, safety and prioritization of interventions and provide a summary of the emerging therapeutic approaches.Recent findingsDuring the past few years, high-quality randomized controlled t...
This article examines the life of this woman, her disease, her identification and the connection with the Duchesse de Guermantes, heroine of LaRecherchedutempsperdu written by Marcel Proust. PMID: 32164973 [PubMed - as supplied by publisher]
ConclusionsThe use of pharmacotherapy options for tic management observed at a specialist clinic for adults with TS reflects guideline recommendations. We found that the presence of co-morbid obsessive-compulsive disorder/behaviours correlates with the choice of anti-dopaminergic medications over alpha-2-agonists, in line with available evidence on the efficacy of anti-dopaminergic medications for the treatment of specific tic –related behavioural symptoms.