Anastomosis stenosis after radical prostatectomy and bladder neck stenosis after benign prostate hyperplasia treatment: reconstructive options.

[Anastomosis stenosis after radical prostatectomy and bladder neck stenosis after benign prostate hyperplasia treatment: reconstructive options]. Urologe A. 2020 Feb 13;: Authors: Rosenbaum CM, Becker B, Gross A, Netsch C Abstract Bladder neck stenosis (BNS) after simple prostatectomy and vesicourethral anastomosis stenosis (VUAS) after radical prostatectomy for prostate cancer are common sequelae. However, the two entities differ in their pathology, anatomy and their surgical results. VUAS has an incidence of 0.2-28%. Commonly, VUAS occurs within the first 2 years after surgery. Initial therapy should be performed endourologically: dilatation, (laser) incision or resection. After three unsuccessful treatment attempts, open reconstruction should be considered. Different surgical approaches (abdominal, perineal, abdominoperineal) have been described. All are associated with good success rates. However, they are accompanied by high rates of urinary incontinence. Incontinence can be treated safely by implantation of an artificial urinary sphincter. The incidence of BNS is around 5% for all types of surgery for benign prostate hyperplasia. It occurs within the first 2 years after surgery. Initial treatment should be performed endourologically. In case of recalcitrant BNS, open reconstruction is indicated. The YV-plasty is an established procedure, and the T‑plasty represents a modification. Success rates of both procedures are high. Robot-as...
Source: Der Urologe. Ausg. A - Category: Urology & Nephrology Authors: Tags: Urologe A Source Type: research

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CONCLUSION: Extensive research have been carried out on various process for preparing Bortezomib and composition thereof. This type of dynamic research will clear the path for many generic players in the United States which lead in reduction of price of the composition and thereby enhancing global health care at cheaper prices. PMID: 32234004 [PubMed - as supplied by publisher]
Source: Recent Patents on Anti-Cancer Drug Discovery - Category: Cancer & Oncology Tags: Recent Pat Anticancer Drug Discov Source Type: research
OBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. METHODS: To investigate vaginal epithelial cell proliferation by Ki-67 antigen expression, persistent estrus was induced in 42 randomly selected rats. These rats were randomly divided into 2 groups: group I (control, n=21), which received 0.1 mL of propylene glycol (vehicle) daily, and group II (experimental, n=21), which received 0...
Source: Clinics - Category: General Medicine Source Type: research
Authors: Okamura K, Bandai S, Fujikawa M, Sato K, Kitazono T Abstract The treatment of Graves' hyperthyroidism (GD) complicated with malignancy is challenging, as anti-thyroid thionamide drugs (ATDs) and anti-cancer chemotherapy are both associated with a risk of neutropenia. Treatment with conventional ATDs, radioactive iodine (RAI) or potassium iodide (KI) was attempted in 8 patients with malignancy (34-80 years of age; 2 males and 6 females) in whom GD had been fortuitously diagnosed during a detailed systematic examination. Three patients requiring surgery were initially treated conventionally with methylmercap...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Conclusions: MF therapy could improve life quality and modulate blood cytokine concentration in advanced lung cancer patients. Hence, it might be applied as an adjuvant therapy along with chemotherapy. PMID: 32238091 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Robot-assisted radical prostatectomy (RARP) has fewer complications as compared to conventional techniques; however, cases of stress urinary incontinence (SUI) and overactive bladder (OAB) are still observed following RARP. Intravesical prostatic protrusion (IPP) has been reported to correlate with dysuria due to benign prostatic hyperplasia. Therefore, in this study, we aimed to assess the potential of IPP as a predictor of the occurrence of postoperative SUI and OAB.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Prostate Cancer: Localized: Surgical Therapy III Source Type: research
As men age, the simple act of urinating can get complicated. Prostate surgery often leaves men vulnerable to leakage when they cough, sneeze, or just rise from a chair. Or the bladder may become impatient, suddenly demanding that you find a bathroom right now. “Thousands of years ago, it was not as much of an issue,” observes Dr. Anurag Das, a urologist at Harvard-affiliated Beth Israel Deaconess Medical Center. “There were lots of trees, and you could just find one and go.” But tricky bladders can be whipped into shape. The first step is a careful assessment of what triggers those difficult moments...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Healthy Aging Incontinence Men's Health Prostate Health Source Type: blogs
By age 60, you have a 50/50 chance of having a clinically enlarged prostate. And it only gets worse every year. When your prostate isn’t functioning properly, it’s hard to enjoy life. Traditional doctors give you two choices. Go under the knife or you take Big Pharma’s drugs. Either way, you have a good chance of ending up with your manhood on the line… If you have surgery, there’s a big risk you’ll be saying goodbye to your sex life for good. The rate of impotence is a shocking 50 to 60% after prostate surgery.1 Big Pharma’s meds to shrink your prostate are no better. These sy...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
AbstractPurpose of ReviewHolmium laser enucleation of the prostate (HoLEP) is a proven technique to alleviate bladder outlet obstruction (BOO) from benign prostatic hyperplasia (BPH). Herein, we review factors relevant to selecting patients who will benefit from this procedure and expected outcomes.Recent FindingsNew randomized trials have validated the excellent outcomes achieved by HoLEP in the management of BOO from BPH. Its success has been reproduced in a diverse array of patients including those on anticoagulation, with detrusor underactivity/acontractility, prostate cancer, and in the retreatment setting.SummaryHoLE...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
Benign prostatic hyperplasia (BPH), or enlargement of the prostate gland, affects about half of men between the age of 51 and 60 and up to 90% of men over the age of 80. Symptoms include difficulty with initiating urination, weak urine flow, post-voi...
Source: Medgadget - Category: Medical Equipment Authors: Tags: Exclusive Urology Source Type: blogs
This study only looked at the effect of dietary or food sources of zinc and not at zinc supplements. Some dietary sources of zinc include the following: • Beef steak - 3 oz contains 4.9 mg • Oysters - 3 oz contains 67 mg • Shrimp - 3 oz contains 1.5 mg • Pork chop - 3 oz contains 2.8 mg • Yogurt - 1 cup contains 2.2 mg • Enriched cereal - ¾ cup contains 15 mg • Red kidney beans - ½ cup contains 2 mg Zinc coming from meat sources is more readily bioavailable than zinc from vegetarian sources. Legumes and whole grains contain phytic acid inhibiting zinc's bioavailability. Co...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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